Title:
PREVENTIVE FOR NEPHROPATHY AND FOOD HAVING THE FUNCTION IMPARTED THERETO
Document Type and Number:
WIPO Patent Application WO/2006/068117
Kind Code:
A1
Abstract:
A composition containing, as the active ingredient, isohumulones or an isomerized hop extract. This composition is useful in treating, preventing or ameliorating organ failures accompanying hypertension, in particular, hypertensive nephropathy or diseases or conditions relating thereto.
Inventors:
KASHIHARA NAOKI (JP)
NAMIKOSHI TAMEHACHI (JP)
YOSHIDA ARUTO (JP)
NAMIKOSHI TAMEHACHI (JP)
YOSHIDA ARUTO (JP)
Application Number:
PCT/JP2005/023326
Publication Date:
June 29, 2006
Filing Date:
December 20, 2005
Export Citation:
Assignee:
KIRIN BREWERY (JP)
KAWASAKI FOUNDATION (JP)
KASHIHARA NAOKI (JP)
NAMIKOSHI TAMEHACHI (JP)
YOSHIDA ARUTO (JP)
KAWASAKI FOUNDATION (JP)
KASHIHARA NAOKI (JP)
NAMIKOSHI TAMEHACHI (JP)
YOSHIDA ARUTO (JP)
International Classes:
A61K31/122; A61K36/60; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P9/12; A61P13/12
Domestic Patent References:
| WO2004064818A1 | 2004-08-05 |
Foreign References:
| JPH06312924A | 1994-11-08 | |||
| JPH04202138A | 1992-07-22 | |||
| JPH092917A | 1997-01-07 | |||
| JPH045237A | 1992-01-09 |
Other References:
TOBE H. ET AL.: "Apoptosis to HL-60 by Humulone", BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, vol. 61, no. 6, 1997, pages 1027 - 1029, XP001189548
TROLLIET M.R., RUDD M.A., LOSCALZO J.: "Oxidative stress and renal dysfunction in salt-sensitive hypertension", KIDNEY BLOOD PRESSURE RESEARCH, vol. 24, 2001, pages 116 - 123, XP002999101
MANNING R.D. JR., MENG S., TIAN N.: "Review Renal and vascular oxidative stress and salt-sensitivity of arterial pressure", ACTA PHYSIOLOGICA SCANDINAVICA, vol. 179, no. 3, 2003, pages 243 - 250, XP002999102
TROLLIET M.R., RUDD M.A., LOSCALZO J.: "Oxidative stress and renal dysfunction in salt-sensitive hypertension", KIDNEY BLOOD PRESSURE RESEARCH, vol. 24, 2001, pages 116 - 123, XP002999101
MANNING R.D. JR., MENG S., TIAN N.: "Review Renal and vascular oxidative stress and salt-sensitivity of arterial pressure", ACTA PHYSIOLOGICA SCANDINAVICA, vol. 179, no. 3, 2003, pages 243 - 250, XP002999102
Attorney, Agent or Firm:
Yoshitake, Kenji (Room 323 Fuji Bldg., 2-3, Marunouchi 3-chom, Chiyoda-ku Tokyo 05, JP)
Download PDF: