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Title:
PREVENTIVE OR REMEDY FOR KIDNEY DISEASES
Document Type and Number:
WIPO Patent Application WO/1997/007806
Kind Code:
A1
Abstract:
A preventive or remedy for kidney diseases comprising as the active ingredient a compound represented by general formula (1), its acid-addition salt or hydrates thereof, wherein R1, R2, R3, R4, R5 and R6 are the same or different and each represents lower alkoxy; and A and A' are the same or different and each represents lower alkylene. The compound has an excellent effect of preventing and treating acute kidney failure, a potent effect of inhibiting ischemia-reflow disorders in the kidney and a low toxicity, which makes it useful in the prevention or treatment of kidney diseases.

Inventors:
YAMAUCHI YOUICHI (JP)
NAKAGAWA TAKASHI (JP)
KAWAGOE JUNICHI (JP)
Application Number:
PCT/JP1996/002341
Publication Date:
March 06, 1997
Filing Date:
August 22, 1996
Export Citation:
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Assignee:
KOWA CO (JP)
YAMAUCHI YOUICHI (JP)
NAKAGAWA TAKASHI (JP)
KAWAGOE JUNICHI (JP)
International Classes:
A61K31/00; A61K31/55; C07D295/096; (IPC1-7): A61K31/55
Foreign References:
JPH0873357A1996-03-19
JPH0859632A1996-03-05
JPH07145060A1995-06-06
EP0710482A21996-05-08
Other References:
See also references of EP 0786254A4
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