Title:
PREVENTIVE AND/OR THERAPEUTIC AGENT FOR ALLODYNIA CAUSED BY ANTICANCER AGENT
Document Type and Number:
WIPO Patent Application WO/2012/137645
Kind Code:
A1
Abstract:
[Problem] To provide a pharmaceutical effective in the prevention and/or treatment of allodynia caused by an anticancer agent.
[Solution] A preventive and/or therapeutic agent for allodynia caused by an anticancer agent, containing natural calcitonin or a calcitonin derivative as an active ingredient is provided. Further, a method for preventing and/or treating allodynia caused by an anticancer agent by administering natural calcitonin or a calcitonin derivative, and the use of natural calcitonin or a calcitonin derivative for producing a preventive and/or therapeutic agent for allodynia caused by an anticancer agent are provided.
Inventors:
ISHII KUNIO (JP)
NAKAHARA TSUTOMU (JP)
SAKAMOTO KENJI (JP)
AOKI MANAHITO (JP)
NAKAHARA TSUTOMU (JP)
SAKAMOTO KENJI (JP)
AOKI MANAHITO (JP)
Application Number:
PCT/JP2012/058148
Publication Date:
October 11, 2012
Filing Date:
March 28, 2012
Export Citation:
Assignee:
ASAHI KASEI PHARMA CORP (JP)
ISHII KUNIO (JP)
NAKAHARA TSUTOMU (JP)
SAKAMOTO KENJI (JP)
AOKI MANAHITO (JP)
ISHII KUNIO (JP)
NAKAHARA TSUTOMU (JP)
SAKAMOTO KENJI (JP)
AOKI MANAHITO (JP)
International Classes:
A61K38/23; A61P25/00; A61P29/00
Domestic Patent References:
| WO2006132261A1 | 2006-12-14 |
Foreign References:
| JP2010533724A | 2010-10-28 | |||
| JP2010524882A | 2010-07-22 | |||
| JP2008280264A | 2008-11-20 |
Other References:
MINORU NARITA ET AL.: "Evaluation method for a pain-like action", FOLIA PHARMACOL. JPN., vol. 130, 2007, pages 124 - 127
JOLIVALT CG ET AL.: "Therapeutic efficacy of prosaposin-derived peptide on different models of allodynia.", PAIN, vol. 121, no. 1-2, March 2006 (2006-03-01), pages 14 - 21, XP025024714, DOI: doi:10.1016/j.pain.2005.11.013
GHELARDINI C ET AL.: "Effects of a new potent analog of tocainide on hNavl.7 sodium channels and in vivo neuropathic pain models.", NEUROSCIENCE, vol. 169, no. 2, 25 August 2010 (2010-08-25), pages 863 - 873
AKITOSHI ITO ET AL.: "Shinkeiinsei Totsu Model ni Okeru Calcitonin no Chintsu Sayo Kijo - OVX Model tono Hikaku", OSTEOPOROSIS, vol. 13, no. 1, 16 September 2005 (2005-09-16), JAPAN, pages 183
APRILE G ET AL.: "Application of distance matrices to define associations between acute toxicities in colorectal cancer patients receiving chemotherapy.", CANCER, vol. 112, no. 2, 15 January 2008 (2008-01-15), pages 284 - 292
YASUSHI KURAISHI: "Calcitonin no Neuropeptide to shiteno Sayo - Chintsu Sayo tono Kanren", KIDNEY AND METABOLIC BONE DISEASES, vol. 14, no. 3, 2001, pages 209 - 217
JOLIVALT CG ET AL.: "Therapeutic efficacy of prosaposin-derived peptide on different models of allodynia.", PAIN, vol. 121, no. 1-2, March 2006 (2006-03-01), pages 14 - 21, XP025024714, DOI: doi:10.1016/j.pain.2005.11.013
GHELARDINI C ET AL.: "Effects of a new potent analog of tocainide on hNavl.7 sodium channels and in vivo neuropathic pain models.", NEUROSCIENCE, vol. 169, no. 2, 25 August 2010 (2010-08-25), pages 863 - 873
AKITOSHI ITO ET AL.: "Shinkeiinsei Totsu Model ni Okeru Calcitonin no Chintsu Sayo Kijo - OVX Model tono Hikaku", OSTEOPOROSIS, vol. 13, no. 1, 16 September 2005 (2005-09-16), JAPAN, pages 183
APRILE G ET AL.: "Application of distance matrices to define associations between acute toxicities in colorectal cancer patients receiving chemotherapy.", CANCER, vol. 112, no. 2, 15 January 2008 (2008-01-15), pages 284 - 292
YASUSHI KURAISHI: "Calcitonin no Neuropeptide to shiteno Sayo - Chintsu Sayo tono Kanren", KIDNEY AND METABOLIC BONE DISEASES, vol. 14, no. 3, 2001, pages 209 - 217
Attorney, Agent or Firm:
IWASE Yoshikazu et al. (JP)
Iwase Yoshiwa (JP)
Iwase Yoshiwa (JP)
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