PREVENTIVES OR REMEDIES FOR DRUG-INDUCED RENAL DISTURBANCE

Title:

PREVENTIVES OR REMEDIES FOR DRUG-INDUCED RENAL DISTURBANCE

Document Type and Number:

WIPO Patent Application WO/1999/043324

Kind Code:

A1

Abstract:

Preventives or remedies for efficaciously preventing or ameliorating drug-induced renal disturbance which contain as the active ingredient compounds represented by general formula (I) or pharmaceutically acceptable salts thereof, wherein R?1¿ and R?2¿ represent each hydrogen or R?1¿ and R?2¿ form together a single bond; and when R?1¿ and R?2¿ represent each hydrogen, then R?3¿ represents CH(OH)CH(OH)CH¿3?, -CH(OCOCH¿3?)CH(OCOCH¿3?)CH¿3?, -CH¿3?, -CH¿2?OH or phenyl, and when R?1¿ and R?2¿ form together a single bond, then R?3¿ is -COCH(OH)CH¿3?.

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Inventors:

OKAMURA MIKIO (JP)
KANAYAMA YOSHIHARU (JP)
YOSHIKAWA JUNICHI (JP)
SHINTAKU HARUO (JP)

Application Number:

PCT/JP1999/000916

Publication Date:

September 02, 1999

Filing Date:

February 26, 1999

Export Citation:

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Assignee:

SUNTORY LTD (JP)
OKAMURA MIKIO (JP)
KANAYAMA YOSHIHARU (JP)
YOSHIKAWA JUNICHI (JP)
SHINTAKU HARUO (JP)

International Classes:

A61K31/519; C07D475/04; (IPC1-7): A61K31/505

Foreign References:

JPS63267781A	1988-11-04
JPS61277618A	1986-12-08
JPS5976086A	1984-04-28
JPS5925323A	1984-02-09

Other References: