Title:
PROBE FOR HUMAN EGFR GENETIC MUTATION DETECTION, KIT AND DETECTION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/059576
Kind Code:
A1
Abstract:
The invention provides a probe for human EGFR genetic mutation detection, a kit and a detection method thereof. The probe comprises one kind or several kinds of probes in 1 to 35 probe pairs. Each probe pair comprises a capture probe and a detection probe, and the nucleotide sequences of the 1 to 35 probe pairs are as shown in SEQ ID NO: 1 to 70. The invention also provides a kit for human EGFR genetic mutation detection.
Inventors:
LIAO WEI (CN)
MO YAQIN (CN)
ZHANG CHENGUANG (CN)
MO YAQIN (CN)
ZHANG CHENGUANG (CN)
Application Number:
PCT/CN2017/104777
Publication Date:
April 05, 2018
Filing Date:
September 30, 2017
Export Citation:
Assignee:
GUANGZHOU EZLIFE SCI & TECH CO LTD (CN)
International Classes:
C12Q1/68; C12N15/11
Domestic Patent References:
| WO2012162613A2 | 2012-11-29 |
Foreign References:
| CN106399518A | 2017-02-15 | |||
| CN205844251U | 2016-12-28 | |||
| CN103517992A | 2014-01-15 | |||
| CN104745679A | 2015-07-01 |
Other References:
WEI, F. ET AL.: "Noninvasive Saliva-based EGFR Gene Mutation Detection in Pa- tients with Lung Cancer", AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE., vol. 190, no. 10, 15 November 2014 (2014-11-15), pages 1117 - 1126, XP055429466, ISSN: 1073-449X, DOI: :10.1164/rccm.201406-1003OC
LIN, C. C.: "Emerging platforms using liquid biopsy to detect EGFR muta- tions in lung cancer", EXPERT REVIEW OF MOLECULAR DIAGNOSTICS., vol. 15, no. 11, 30 September 2015 (2015-09-30), pages 1427 - 1440, XP055603167, ISSN: 1473-7159, DOI: 10.1586/14737159.2015.1094379
WEI, F.ET AL.: "Electrochemical Sensor for Multiplex Biomarkers Detection", CLINICAL CANCER RESEARCH, vol. 15, no. 13, 1 July 2009 (2009-07-01), pages 4446 - 4452, XP055139487, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-09-0050
LIN, C. C.: "Emerging platforms using liquid biopsy to detect EGFR muta- tions in lung cancer", EXPERT REVIEW OF MOLECULAR DIAGNOSTICS., vol. 15, no. 11, 30 September 2015 (2015-09-30), pages 1427 - 1440, XP055603167, ISSN: 1473-7159, DOI: 10.1586/14737159.2015.1094379
WEI, F.ET AL.: "Electrochemical Sensor for Multiplex Biomarkers Detection", CLINICAL CANCER RESEARCH, vol. 15, no. 13, 1 July 2009 (2009-07-01), pages 4446 - 4452, XP055139487, ISSN: 1078-0432, DOI: 10.1158/1078-0432.CCR-09-0050
Attorney, Agent or Firm:
HAIHONG JIACHENG INTELLECTUAL PROPERTY & PARTNERS (CN)
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