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Title:
PROBIOTICS FOR BIOLOGICAL CONTROL AGAINST VIBRIO SP.
Document Type and Number:
WIPO Patent Application WO/2012/105805
Kind Code:
A3
Abstract:
The present invention relates to probiotics for biological control against Vibrio sp., and in particular, to a newly isolated bacillus strain that degrades quorum-sensing signal molecules of the pathogenic bacteria Vibrio sp., and inhibits biofilm formation; a culture broth obtained by culturing the strain, a concentrate thereof, or a dry product thereof; a probiotic composition, a feed additive, an antimicrobial agent, or a water quality improving agent comprising the strain, the culture broth thereof, the concentrate thereof, or the dry product thereof; and a method for culturing fish or crustaceans, degrading quorum-sensing signal molecules of Vibrio harveyi and inhibiting biofilm formation, preventing bacterial infection in animals and improving water quality using the strain, the culture broth thereof, the concentrate thereof, or the dry product thereof.

Inventors:
YANG SI YONG (KR)
WOO SEO HYUNG (KR)
KANG IN HYE (KR)
IM HYUN JUNG (KR)
Application Number:
PCT/KR2012/000763
Publication Date:
December 20, 2012
Filing Date:
January 31, 2012
Export Citation:
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Assignee:
CJ CHEILJEDANG CORP (KR)
YANG SI YONG (KR)
WOO SEO HYUNG (KR)
KANG IN HYE (KR)
IM HYUN JUNG (KR)
International Classes:
C12N1/20; A01N63/22; A23K1/16
Foreign References:
KR100685237B12007-02-22
Other References:
B. VASEEHARAN ET AL.: "Control of pathogenic Vibrio spp. by Bacillus subtilis BT23, a possible probiotic treatment for black tiger shrimp Penaeus monodon", LETTERS IN APPLIED MICROBIOLOGY., vol. 36, no. 2, 2003, pages 83 - 87
ADITYA KESARCODI-WATSON ET AL.: "Probiotics in aquaculture: The need, principles and mechanisms of action and screening processes", AQUACULTURE., vol. 274, no. 1, January 2008 (2008-01-01), pages 1 - 14
T. NAKAYAMA ET AL.: "Inhibitory effects of Bacillus probionts on growth and toxin production of Vibrio harveyi pathogens of shrimp", LETTERS IN APPLIED MICROBIOLOGY., vol. 49, no. 6, December 2009 (2009-12-01), pages 679 - 684
J. E. HILL ET AL.: "Isolation of a novel strain of Bacillus pumilus from penaeid shrimp that is inhibitory against marine pathogens", JOURNAL OF FISH DISEASES, vol. 32, no. 12, December 2009 (2009-12-01), pages 1007 - 1016
FANGFANG BAI ET AL.: "Disruption of quorum sensing in Vibrio harveyi by the AiiA protein of Bacillus thuringiensis", AQUACULTURE., vol. 274, no. 1, 31 January 2008 (2008-01-31), pages 36 - 40
YONG SEOK LEE ET AL.: "Removal of ammonia and nitrite in water by Bacillus sp. A8-8", KOREAN JOURNAL OF LIFE SCIENCE., vol. 13, no. 1, February 2003 (2003-02-01), pages 47 - 53
Attorney, Agent or Firm:
SON, Min (6th Floor, City Air Tower, 36, Teheran-ro 87 gil,,Samsung-dong, Gangnam-gu, Seoul 135-973, KR)
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