PROBIOTICS-DELIVERING HYDROGEL FORMULATION FOR PROTECTING PROBIOTICS IN ACIDIC ENVIRONMENT AND COMPOSITION FOR DELIVERING PROBIOTICS COMPRISING SAME

Title:

PROBIOTICS-DELIVERING HYDROGEL FORMULATION FOR PROTECTING PROBIOTICS IN ACIDIC ENVIRONMENT AND COMPOSITION FOR DELIVERING PROBIOTICS COMPRISING SAME

Document Type and Number:

WIPO Patent Application WO/2018/230939

Kind Code:

A1

Abstract:

The present invention relates to a hydrogel formulation for delivering probiotics comprising, as active ingredients, a hydrogel, probiotics, and a zwitterionic buffer; a composition for delivering probiotics comprising the same; and a preparation method therefor. The present invention can control and maintain the pH level within the hydrogel even in a gastric fluid environment by further adding the zwitterionic buffer which is capable of maintaining the pH level in the hydrogel encapsulating the probiotics, thereby increasing a survival rate of the probiotics in the gastric fluid and improving a rate of delivery to the large intestine.

More Like This:

WO/2013/168852	MICRO ROBOT FOR IN VIVO DRUG DELIVERY, APPARATUS FOR CONTROLLING SAME AND DRUG DELIVERY METHOD USING SAME
WO/2012/022920	DEVICE THAT IS IMPLANTABLE IN THE TEMPORAL BONE FOR DELIVERING A MATERIAL, AND HEARING AID PROVIDED WITH SUCH A DEVICE
JPH07507566	[Title of the Invention] Method and apparatus for encapsulating a substance

Inventors:

YOO JIN-WOOK (KR)
KIM JI HYUN (KR)

Application Number:

PCT/KR2018/006652

Publication Date:

December 20, 2018

Filing Date:

June 12, 2018

Export Citation:

Click for automatic bibliography generation Help

Assignee:

NAT UNIV PUSAN IND UNIV COOP FOUND (KR)

International Classes:

A61K9/50; A61K9/06; A61K9/16; A61K35/747; A61K47/18; A61K47/36

Foreign References:

KR101000952B1	2010-12-13
KR20090076438A	2009-07-13
JP5950938B2	2016-07-13
KR20000043838A	2000-07-15

Other References:

MATHEWS, SMITHA: "Microencapsulation of probiotics by calcium alginate and gelatin and evaluation of its survival in simulated human gastro-intestinal condition", JOURNAL OF CURRENT MICROBIOLOGY AND APPLIED SCIENCES, vol. 6, no. 4, 10 April 2017 (2017-04-10), pages 2080 - 2087, XP055435578, DOI: 10.20546/ijcmas.2017.604.245

Attorney, Agent or Firm:

TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (KR)

Download PDF:

View/Download PDF PDF Help

Previous Patent: HLA-A2 SUBTYPE-SPECIFIC PLK1-DERIVED EPITOPE INDUCING ANTIGEN-SPECIFIC T CELL IMMUNE RESPONSE TO PLK...

Next Patent: STRETCHABLE SUBSTRATE STRUCTURE AND MANUFACTURING METHOD THEREFOR, STRETCHABLE DISPLAY AND MANUFACTU...