Title:
PROBUCOL DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/149091
Kind Code:
A1
Abstract:
The present invention relates to the field of compounds, and in particular to a probucol derivative, a preparation method therefor and use thereof, the probucol derivative having a structure represented by general formula I. The probucol derivative provided in the present invention can be used for the prevention and treatment of vascular diseases including diabetes, cardio-cerebrovascular diseases or complications thereof, and can be effectively used for reducing blood glucose, reducing blood lipid, reducing cholesterol, reducing body weight, reducing triglyceride, anti-inflammatory, anti-oxidation, etc., having broad prospective applications.
Inventors:
LV SONG (CN)
XIE WENWEI (CN)
HE SHUANGJIANG (CN)
XIE WENWEI (CN)
HE SHUANGJIANG (CN)
Application Number:
PCT/CN2019/072315
Publication Date:
August 08, 2019
Filing Date:
January 18, 2019
Export Citation:
Assignee:
DEMOTECH INC (CN)
International Classes:
C07C323/52; A61K31/10; A61K31/192; A61K31/216; A61P1/16; A61P3/10; C07D249/08; C07D295/088; C07D311/58; C07D339/04; C07D495/04
Domestic Patent References:
WO2011019747A1 | 2011-02-17 | |||
WO2007044726A2 | 2007-04-19 | |||
WO2007142581A1 | 2007-12-13 | |||
WO1998009781A1 | 1998-03-12 | |||
WO2007044726A2 | 2007-04-19 |
Foreign References:
CN108299263A | 2018-07-20 | |||
US20030176511A1 | 2003-09-18 | |||
CN101686676A | 2010-03-31 | |||
CN101284808A | 2008-10-15 | |||
US3862332A | 1975-01-21 | |||
US4985465A | 1991-01-15 | |||
CN200810246677A | 2008-12-29 | |||
CN201610591938A | 2016-07-26 | |||
CN200880007795A | 2008-03-07 | |||
US5262439A | 1993-11-16 | |||
US9650332B1 | 2017-05-16 | |||
CN201710107801A | 2017-02-27 | |||
US20030064967A1 | 2003-04-03 | |||
CN98807171A | 1998-05-14 | |||
US6121319A | 2000-09-19 | |||
CN200880016419A | 2008-03-26 | |||
CN200810167035A | 2008-10-09 |
Other References:
See also references of EP 3747863A4
Attorney, Agent or Firm:
CN-KNOWHOW INTELLECTUAL PROPERTY AGENT LIMITED (CN)
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