Title:
PROCESS FOR DEUTERATION OF INERT METHYLENE
Document Type and Number:
WIPO Patent Application WO/2003/104166
Kind Code:
A1
Abstract:
The invention relates to a process for deuteration of inert alkanes with activated palladium−carbon, specifically, a process for deuterating a compound having either a methyl group or an alkylene group having two or more carbon atoms in a state directly bonded to an optionally substituted aromatic ring through replacement of one or more hydrogen atoms of the methyl group or one or more of the benzylic and other hydrogen atoms of the alkylene group by deuterium, characterized in that the above compound is subjected to refluxing in a closed system in the presence of activated palladium−carbon in a state dissolved in a deuterated solvent.
Inventors:
HIROTA KOSAKU (JP)
SAJIKI HIRONAO (JP)
SAJIKI HIRONAO (JP)
Application Number:
PCT/JP2002/011785
Publication Date:
December 18, 2003
Filing Date:
November 12, 2002
Export Citation:
Assignee:
WAKO PURE CHEM IND LTD (JP)
HIROTA KOSAKU (JP)
SAJIKI HIRONAO (JP)
HIROTA KOSAKU (JP)
SAJIKI HIRONAO (JP)
International Classes:
C07B59/00; (IPC1-7): C07B59/00
Foreign References:
| JPS63198638A | 1988-08-17 | |||
| EP0203588A2 | 1986-12-03 | |||
| JPH10139694A | 1998-05-26 |
Attorney, Agent or Firm:
WAKO PURE CHEMICAL INDUSTRIES, LTD. (Chuo-ku, Tokyo, JP)
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