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Title:
A PROCESS FOR FERMENTING CO-CONTAINING GASEOUS SUBSTRATES
Document Type and Number:
WIPO Patent Application WO/2014/126940
Kind Code:
A3
Abstract:
A process provides high ethanol productivity levels during fermentation of a CO-containing substrate. The process controls CO-substrate feed rates and cell density to avoid culture upset and CO inhibition. The process includes fermenting a CO-containing gaseous substrate to obtain a target cell density and a target CO feed rate, and then periodically reducing and increasing the CO feed rate.

Inventors:
BELL PETER SIMPSON (GB)
LIU SONG (US)
Application Number:
PCT/US2014/015892
Publication Date:
November 06, 2014
Filing Date:
February 11, 2014
Export Citation:
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Assignee:
INEOS BIO SA (CH)
BELL PETER SIMPSON (GB)
LIU SONG (US)
International Classes:
C12P7/06
Domestic Patent References:
WO2002008438A22002-01-31
WO2009151342A12009-12-17
Other References:
MICHAEL KÖPKE ET AL: "Fermentative production of ethanol from carbon monoxide", CURRENT OPINION IN BIOTECHNOLOGY, vol. 22, no. 3, 1 June 2011 (2011-06-01), pages 320 - 325, XP055104855, ISSN: 0958-1669, DOI: 10.1016/j.copbio.2011.01.005
MUNASINGHE P C ET AL: "Biomass-derived syngas fermentation into biofuels: Opportunities and challenges", BIORESOURCE TECHNOLOGY, ELSEVIER BV, GB, vol. 101, no. 13, 1 July 2010 (2010-07-01), pages 5013 - 5022, XP026986241, ISSN: 0960-8524, [retrieved on 20100327]
S.S. RIGGS ET AL: "Measuring Carbon Monoxide Gas-Liquid Mass Transfer in a Stirred Tank Reactor for Syngas Fermentation", BIOTECHNOLOGY PROGRESS, vol. 22, no. 3, 2 June 2006 (2006-06-02), pages 903 - 906, XP055095229, ISSN: 8756-7938, DOI: 10.1021/bp050352f
COTTER J L ET AL: "Influence of process parameters on growth of Clostridium ljungdahlii and Clostridium autoethanogenum on synthesis gas", ENZYME AND MICROBIAL TECHNOLOGY, STONEHAM, MA, US, vol. 44, no. 5, 6 May 2009 (2009-05-06), pages 281 - 288, XP026004172, ISSN: 0141-0229, [retrieved on 20081117], DOI: 10.1016/J.ENZMICTEC.2008.11.002
MAEDEH MOHAMMADI ET AL: "Kinetic Studies on Fermentative Production of Biofuel from Synthesis Gas Using Clostridium ljungdahlii", THE SCIENTIFIC WORLD JOURNAL, vol. 27, no. 2, 1 January 2014 (2014-01-01), pages 185 - 8, XP055122952, ISSN: 2356-6140, DOI: 10.1016/j.biortech.2005.05.014
Attorney, Agent or Firm:
KRUEGER, James P (3030 Warrenville RoadSuite 65, Lisle Illinois, US)
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