Title:
PROCESS AND INTERMEDIATES FOR THE PREPARATION OF ISOXAZOLECAROXAMIDES AND ANALOGUES
Document Type and Number:
WIPO Patent Application WO2001014576
Kind Code:
B1
Abstract:
Efficient synthetic routes for the preparation of rhinovirus protease inhibitors of formula (I), particulary (I'), key intermediates useful in those synthetic routes, as well as a continuous membrane reactor useful for those synthetic routes. These compounds of formula (I), as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses.
Inventors:
TAO JUNHUA
BABU SRINIVASAN
DAGNINO RAYMOND JR
TIAN QINGPING
REMARCHUK TRAVIS PAUL
MCGEE KEVIN SCOTT
NAYYAR NARESH K
MORAN TERENCE JAROLD
BABU SRINIVASAN
DAGNINO RAYMOND JR
TIAN QINGPING
REMARCHUK TRAVIS PAUL
MCGEE KEVIN SCOTT
NAYYAR NARESH K
MORAN TERENCE JAROLD
Application Number:
PCT/US2000/023032
Publication Date:
September 27, 2001
Filing Date:
August 23, 2000
Export Citation:
Assignee:
AGOURON PHARMA (US)
International Classes:
A61K31/422; A61P31/14; B01J19/24; C07C69/732; C07C229/34; C07C271/22; C07C303/28; C07D207/26; C07D261/18; C07D413/12; C12M1/12; C12P7/42; C12P17/14; C07C309/65; (IPC1-7): C07D413/12; C07D261/18; C07C309/65; C07C303/28; C07C69/732; C07C59/56; C07C271/22; C07C229/36; C07C51/347; C12P17/14; C12P7/42; C12P1/00
Download PDF: