Title:
PROCESS FOR MAKING GEL FILMS
Document Type and Number:
WIPO Patent Application WO2004091537
Kind Code:
B1
Abstract:
The present invention is directed to a process for making homogeneous, thermoreversible gel films comprising the steps of: (i) heating, hydrating, mixing, solubilizing, and, optionally, de-aerating a high solids, low moisture film forming composition in an apparatus providing sufficient shear, temperature and residence time to form a homogeneous molten composition, wherein the temperature is at or above the solubilizing temperature of said composition; (ii) feeding the molten composition into at least one of a mixer, pump or devolatilizer; and (iii) cooling the homogeneous molten composition at or below its gelling temperature to form said gel films. The present invention is also directed to various products made from such films, such as the gel films themselves, soft capsules, solid dosage forms and delivery systems.
Inventors:
BALLARD ARTHUR D (US)
SEWALL CHRISTOPHER J (US)
MODLISZEWSKI JAMES J (US)
BLAKEMORE WILLIAM R (US)
RILEY PETER J (US)
SEWALL CHRISTOPHER J (US)
MODLISZEWSKI JAMES J (US)
BLAKEMORE WILLIAM R (US)
RILEY PETER J (US)
Application Number:
PCT/US2004/011906
Publication Date:
July 14, 2005
Filing Date:
April 14, 2004
Export Citation:
Assignee:
FMC CORP (US)
BALLARD ARTHUR D (US)
SEWALL CHRISTOPHER J (US)
MODLISZEWSKI JAMES J (US)
BLAKEMORE WILLIAM R (US)
RILEY PETER J (US)
BALLARD ARTHUR D (US)
SEWALL CHRISTOPHER J (US)
MODLISZEWSKI JAMES J (US)
BLAKEMORE WILLIAM R (US)
RILEY PETER J (US)
International Classes:
A01N43/04; A23L27/00; A23L29/20; A23L29/256; A61K8/11; A61K8/73; A61K9/00; A61K9/14; A61K9/48; A61K31/715; A61K31/737; A61K47/00; A61Q19/00; A61Q90/00; B01F5/02; A61K; (IPC1-7): A61K9/00; A61K9/48
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