PROCESS FOR THE PREPARATION OF 4-(3-CHLORO-2-FLUORO-ANILINO)-7-METHOXY-6-[1-(N-METHYLCARBAMOYLMETHYL)-PIPERIDIN-4-YL]QUINAZOLINE

Title:

PROCESS FOR THE PREPARATION OF 4-(3-CHLORO-2-FLUORO-ANILINO)-7-METHOXY-6-[1-(N-METHYLCARBAMOYLMETHYL)-PIPERIDIN-4-YL]QUINAZOLINE

Document Type and Number:

WIPO Patent Application WO/2010/122340

Kind Code:

A3

Abstract:

Processes for the preparation of 4-(3-chloro-2-fluoroanilino)-7-methoxy-6-{[1-(N- methylcarbamoylmethyl)piperidin-4-yl]oxy}quinazoline, salts thereof, and the intermediates used in the process are described.

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Inventors:

BOARDMAN KAY ALISON (GB)
CUNNINGHAM OLIVER ROBERT (GB)
GOUNDRY WILLIAM (GB)
LAFFAN DAVID DERMOT PATRICK (GB)

Application Number:

PCT/GB2010/050653

Publication Date:

September 09, 2011

Filing Date:

April 22, 2010

Export Citation:

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Assignee:

ASTRAZENECA AB (SE)
ASTRAZENECA UK LTD (GB)
BOARDMAN KAY ALISON (GB)
CUNNINGHAM OLIVER ROBERT (GB)
GOUNDRY WILLIAM (GB)
LAFFAN DAVID DERMOT PATRICK (GB)

International Classes:

C07C257/12; C07D211/46; C07D401/12

Domestic Patent References:

WO2005028469A1	2005-03-31
WO2005115145A2	2005-12-08
WO2005023783A1	2005-03-17
WO2009138781A1	2009-11-19
WO2009138779A1	2009-11-19

Other References:

DATABASE CASREACT [online] CHEMICAL ABSTRACTS SERVICES, COLUMBUS, OHIO, US; 2007, XP002603411, Database accession no. 148:331709

Attorney, Agent or Firm:

ASTRAZENECA INTELLECTUAL PROPERTY (Södertälje, SE)

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