Title:
PROCESS FOR THE PREPARATION OF CRISABOROLE AND ITS INTERMEDIATES
Document Type and Number:
WIPO Patent Application WO/2019/138422
Kind Code:
A1
Abstract:
The present invention provides a novel and improved process for the preparation of Crisaborole of Formula (I) and its pharmaceutically acceptable salts. The present invention also provides novel intermediates and process for the preparation of intermediates used in the preparation of Crisaborole. The present invention also provides an improved process for the preparation of Crisaborole and pharmaceutically acceptable salts thereof, that is commercially and industrially scalable.
Inventors:
MERCHANT RUPA SUDHIR (IN)
MERCHANT ADITYA SUDHIR (IN)
LIMBAD PIYUSHKUMAR BHIKHALAL (IN)
PANSURIYA AKSHAY MADHUBHAI (IN)
VAVAIYA BHAVIN MADHAVJIBHAI (IN)
FALDU JASMIN JAYSUKHLAL (IN)
MERCHANT ADITYA SUDHIR (IN)
LIMBAD PIYUSHKUMAR BHIKHALAL (IN)
PANSURIYA AKSHAY MADHUBHAI (IN)
VAVAIYA BHAVIN MADHAVJIBHAI (IN)
FALDU JASMIN JAYSUKHLAL (IN)
Application Number:
PCT/IN2019/050002
Publication Date:
July 18, 2019
Filing Date:
January 01, 2019
Export Citation:
Assignee:
HALCYON LABS PRIVATE LTD (IN)
International Classes:
C07F5/04
Foreign References:
| US9682092B2 | 2017-06-20 |
Other References:
REZA FAREGHI ALAMDARI: "A solvent free and selective method for preparation of triphenylmethyl ethers of alcohols and nucleosides", BULLETIN OF THE CHEMICAL SOCIETY OF ETHIOPIA, vol. 24, no. 2, 22 February 2010 (2010-02-22), pages 299 - 304, XP055624879, Retrieved from the Internet
SUN JING, ET AL.: "A Method for the Deprotection of Alkylpinacolyl Boronate Esters", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 76, no. 9, 30 March 2011 (2011-03-30), pages 3571 - 3575, XP055624883, Retrieved from the Internet
SUN JING, ET AL.: "A Method for the Deprotection of Alkylpinacolyl Boronate Esters", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 76, no. 9, 30 March 2011 (2011-03-30), pages 3571 - 3575, XP055624883, Retrieved from the Internet
Attorney, Agent or Firm:
MENDA, Manoj G. (IN)
Download PDF:
Previous Patent: ELASTIC FASTENING ASSEMBLY FOR RAILWAY RAIL
Next Patent: DIRECT BRAILLE SLATE WITH SLATE BASE, SLATE FRAME AND LINE GUIDE UNIT
Next Patent: DIRECT BRAILLE SLATE WITH SLATE BASE, SLATE FRAME AND LINE GUIDE UNIT