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Title:
PROCESS FOR THE PREPARATION OF ESTETROL AND RELATED COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2013/034780
Kind Code:
A3
Abstract:
The invention relates to a process for obtaining Estetrol and derivatives thereof of formula (I) or a salt or solvate thereof, wherein R represents H or anhydroxyl protecting group; the process comprising reacting a compound of formula (II) or a salt or solvate thereof, wherein R is as defined previously, with an oxidizing agent; the invention also relates to said 3-OH protected derivatives of formula (I) and intermediate products useful in the process.

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Inventors:
FERREIRO GIL JUAN JOSE (ES)
IGLESIAS RETUERTO JESUS MIGUEL (ES)
GALLO NIETO FRANCISCO JAVIER (ES)
Application Number:
PCT/EP2012/076358
Publication Date:
October 03, 2013
Filing Date:
December 20, 2012
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Assignee:
CRYSTAL PHARMA SAU (ES)
International Classes:
C07J1/00; C07J51/00
Domestic Patent References:
WO2004041839A22004-05-21
WO2013050553A12013-04-11
Foreign References:
EP2383279A12011-11-02
Attorney, Agent or Firm:
ARIAS SANZ, Juan (S.L.Avenida de Burgos, 16, Edificio Euromor Madrid, ES)
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