Title:
PROCESS FOR THE PREPARATION OF HIGHLY PURE CEFUROXIME AXETIL
Document Type and Number:
WIPO Patent Application WO/2003/014126
Kind Code:
A1
Abstract:
A process for the preparation of highly pure cefuroxime axetil is herein described. The process makes use of a treatment, which allows removing an impurity present in the reagent l-acetoxyethyl bromide and responsible for the formation of cefuroxime dimeric derivatives. The removal of said impurity makes it easier to recover crystalline cefuroxime axetil and allows obtaining an exceptional-quality product.
Inventors:
FELISI CLAUDIO (IT)
LONGONI DAVIDE (IT)
ALPEGIANI MARCO (IT)
CABRI WALTER (IT)
LONGONI DAVIDE (IT)
ALPEGIANI MARCO (IT)
CABRI WALTER (IT)
Application Number:
PCT/EP2002/008583
Publication Date:
February 20, 2003
Filing Date:
August 01, 2002
Export Citation:
Assignee:
ANTIBIOTICOS SPA (IT)
FELISI CLAUDIO (IT)
LONGONI DAVIDE (IT)
ALPEGIANI MARCO (IT)
CABRI WALTER (IT)
FELISI CLAUDIO (IT)
LONGONI DAVIDE (IT)
ALPEGIANI MARCO (IT)
CABRI WALTER (IT)
International Classes:
C07D501/00; C07D501/14; C07D501/34; (IPC1-7): C07D501/34
Foreign References:
| GB2145409A | 1985-03-27 | |||
| US5847118A | 1998-12-08 | |||
| US4820833A | 1989-04-11 | |||
| US4562181A | 1985-12-31 | |||
| US4267320A | 1981-05-12 | |||
| US5013833A | 1991-05-07 | |||
| US4775750A | 1988-10-04 | |||
| US4994567A | 1991-02-19 |
Attorney, Agent or Firm:
Banfi, Paolo (Via Rossini 8, Milano, IT)
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