Title:
A PROCESS FOR PREPARATION OF MIVACURIUM CHLORIDE
Document Type and Number:
WIPO Patent Application WO/2013/021398
Kind Code:
A3
Abstract:
The present invention discloses a novel, cost-effective process for preparation of [R-[R*,R*-(E)]]-2,2'-(l,8-dioxo-4-octene-l,8-diyl) bis(oxy- 3, 1-propanediyl) bis(l,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-l-[(3,4,5- trimethoxyphenyl)- methyl] isoquinolinium) dichloride, commonly known as mivacurium chloride, which avoids the conversion of (E)-4-octene-l,8-dioic acid to its acid chloride and use of non-ionic polymeric adsorbent resin to get a highly pure product.
Inventors:
MANJATHURU MAHALINGA (IN)
MAYEKAR ANIL NARAYAN (IN)
DERAMBALA YOGEESH (IN)
VASUDEVA PEJAKALA KAKRANNAYA (IN)
ARULMOLI THANGAVEL (IN)
DAS GAUTAM KUMAR (IN)
MAYEKAR ANIL NARAYAN (IN)
DERAMBALA YOGEESH (IN)
VASUDEVA PEJAKALA KAKRANNAYA (IN)
ARULMOLI THANGAVEL (IN)
DAS GAUTAM KUMAR (IN)
Application Number:
PCT/IN2012/000540
Publication Date:
March 14, 2013
Filing Date:
August 03, 2012
Export Citation:
Assignee:
SEQUENT SCIENT LTD (IN)
MANJATHURU MAHALINGA (IN)
MAYEKAR ANIL NARAYAN (IN)
DERAMBALA YOGEESH (IN)
VASUDEVA PEJAKALA KAKRANNAYA (IN)
ARULMOLI THANGAVEL (IN)
DAS GAUTAM KUMAR (IN)
MANJATHURU MAHALINGA (IN)
MAYEKAR ANIL NARAYAN (IN)
DERAMBALA YOGEESH (IN)
VASUDEVA PEJAKALA KAKRANNAYA (IN)
ARULMOLI THANGAVEL (IN)
DAS GAUTAM KUMAR (IN)
International Classes:
C07D217/00
Foreign References:
| US4761418A | 1988-08-02 | |||
| US20070293534A1 | 2007-12-20 | |||
| US4491665A | 1985-01-01 |
Attorney, Agent or Firm:
KUMAR, Ramesh (120 A&B Industrial Area,,Baikampady, New Mangalor, Karnataka ., IN)
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