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Title:
PROCESS FOR PREPARING AMINOTHIAZOLYLACETIC ACID DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/1984/002703
Kind Code:
A1
Abstract:
A process for preparing novel aminothiazolylacetic acid derivatives useful as intermediates for synthesizing beta-lactam antibiotics, starting with diketene as shown in formula (I), wherein R represents lower alkyl or phenyl, R1 and R2 each represents hydrogen or lower alkyl, and X and X' each represents halogen.

Inventors:
TAKANOHASHI KUNIO (JP)
YOSHIDA TSUNEAKI (JP)
FUJII SHOICHIRO (JP)
Application Number:
PCT/JP1983/000003
Publication Date:
July 19, 1984
Filing Date:
January 07, 1983
Export Citation:
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Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD (JP)
International Classes:
C07D277/20; C07D277/40; C07D277/74; C07D417/12; C07D417/14; C07D501/20; (IPC1-7): C07D277/40
Foreign References:
JPS5598189A1980-07-25
Other References:
Miklos Bodanszky et al: "Peptide Synthesis" second edition (1976) John Wiley and sons Inc., (U.S.A.) P. 54-56
Journal of Pharmaceutical Science, Vol. 59, No. 1 (January, 1970) (U.S.A.) A. Kapoor: "Recent Trends in the Synthesis of Linear Peptides" P. 1-27
Journal of Chemical Society, No. 97 (1910) F. Chick et al: "The Polymerisation of Keten. Cyclobutan - 1 : 3 - dione ("Acetylketen") P. 1978-2000
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