Title:
PROCESS FOR PREPARING CROSS-BRIDGED TETRAAZA MACROCYCLES
Document Type and Number:
WIPO Patent Application WO2000032601
Kind Code:
A3
Abstract:
The present invention relates to a process for preparing a cross-bridged tetraaza macrocyclic ligand having formula (I) wherein each R is independently C1-C8 linear or branched alkyl, -(CH2)xCO2M, and mixtures thereof; provided both of the R units are not methyl; M is hydrogen or a salt forming cation; x is from 1 to 6; each index n is independently from 0 to 3; by contacting a di-quaternary cis tetracycle precursor with hydrogen in the presence of a palladium catalyst in an aqueous solution having a pH of at least about 10 at a temperature of about 40 DEG C to about 100 DEG C.
Inventors:
HILER GEORGE DOUGLAS II (US)
PERKINS CHRISTOPHER MARK (US)
PERKINS CHRISTOPHER MARK (US)
Application Number:
PCT/US1999/027316
Publication Date:
October 05, 2000
Filing Date:
November 18, 1999
Export Citation:
Assignee:
PROCTER & GAMBLE (US)
HILER GEORGE DOUGLAS II (US)
PERKINS CHRISTOPHER MARK (US)
HILER GEORGE DOUGLAS II (US)
PERKINS CHRISTOPHER MARK (US)
International Classes:
B01J31/18; C07B61/00; C07D487/08; C07F13/00; (IPC1-7): C07D487/08; B01J31/18; C07F13/00
Domestic Patent References:
| WO1998039335A1 | 1998-09-11 | |||
| WO1998039098A1 | 1998-09-11 |
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