Title:
PROCESS FOR PREPARING SYNTHETIC PROSTACYCLINS
Document Type and Number:
WIPO Patent Application WO/2013/040068
Kind Code:
A3
Abstract:
The presently disclosed subject matter provides methods of preparing synthetic prostacyclin analogues, including Beraprost, either as racemic mixtures or as single stereoisomers. Also provided are novel synthetic intermediates for use in these methods.
Inventors:
YIANNIKOUROS GEORGE PETROS (US)
KALARITIS PANOS (US)
GAMAGE CHAMINDA PRIYAPUSHPA (US)
AREFYEV DENIS VIKTOROVICH (US)
KALARITIS PANOS (US)
GAMAGE CHAMINDA PRIYAPUSHPA (US)
AREFYEV DENIS VIKTOROVICH (US)
Application Number:
PCT/US2012/054910
Publication Date:
May 16, 2013
Filing Date:
September 12, 2012
Export Citation:
Assignee:
IRIX PHARMACEUTICALS INC (US)
YIANNIKOUROS GEORGE PETROS (US)
KALARITIS PANOS (US)
GAMAGE CHAMINDA PRIYAPUSHPA (US)
AREFYEV DENIS VIKTOROVICH (US)
YIANNIKOUROS GEORGE PETROS (US)
KALARITIS PANOS (US)
GAMAGE CHAMINDA PRIYAPUSHPA (US)
AREFYEV DENIS VIKTOROVICH (US)
International Classes:
C07D307/93; A61K31/343; C07C59/125; C07C405/00
Domestic Patent References:
| WO2003011849A1 | 2003-02-13 |
Foreign References:
| US20020087025A1 | 2002-07-04 | |||
| US4311644A | 1982-01-19 | |||
| JPH0662600B2 | 1994-08-17 |
Attorney, Agent or Firm:
TAYLOR, Arles, A., Jr. (Wilson Taylor & Hunt, P.A.,Suite 1200, University Tower,3100 Tower Boulevar, Durham NC, US)
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