Title:
PROCESS FOR PRODUCING 3-ALKENYLCEPHEM COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/1998/055485
Kind Code:
A1
Abstract:
A process for producing 3-alkenylcephem compounds represented by general formula (3) characterized in that an iodination reagent, an alkali metal hydroxide or carbonate, an arylphosphine, and an aldehyde represented by the general formula (2): R?4�-CHO are caused to simultaneously act on a 3-chloromethylcephem compound represented by general formula (1) to thereby produce the target compound in one step, wherein R?1�, R?2�, R?3� and R?4� are each as defined in the description.
Inventors:
KAMEYAMA YUTAKA (JP)
Application Number:
PCT/JP1998/002463
Publication Date:
December 10, 1998
Filing Date:
June 04, 1998
Export Citation:
Assignee:
OTSUKA KAGAKU KK (JP)
KAMEYAMA YUTAKA (JP)
KAMEYAMA YUTAKA (JP)
International Classes:
C07D501/00; C07D501/04; C07D501/22; C07D501/24; (IPC1-7): C07D501/04
Foreign References:
| JPS61269330A | 1986-11-28 | |||
| JPS6320435B2 | 1988-04-27 | |||
| JPH03120288A | 1991-05-22 | |||
| JPH069646A | 1994-01-18 |
Other References:
See also references of EP 0990656A4
Attorney, Agent or Firm:
Tamura, Iwao (4-5-103 Terauchi 1-chom, Toyonaka-shi Osaka-fu, JP)
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