PROCESS FOR PRODUCING 3-AMINO-2-HYDROXYPROPIONIC ACID DERIVATIVES

Title:

PROCESS FOR PRODUCING 3-AMINO-2-HYDROXYPROPIONIC ACID DERIVATIVES

Document Type and Number:

WIPO Patent Application WO/2002/000601

Kind Code:

A1

Abstract:

An economically advantageous and industrially appropriate process for producing 3-amino-2-hydroxypropionic acid derivatives (1) without resort to any dangerous reagents characterized by comprising treating an N-protected-3-amino-2-hdyroxypropionic acid derivative (2) having a contrary configuration at the carbon atom at the 2-position to a compound (1) with an agent for introducing a leaving group to thereby convert the compound (2) into an N-protected-3-amino-propionic acid derivative (3), then treating the compound (3) with a basic substance to give a substituted 3-amino-2-hydroxypropionic acid derivative (4) having an inversed configuration at the carbon atom at the 2-psoition, and then converting the compound (4) into the 3-amino-2-hydroxypropionic acid derivative (1).

Inventors:

MURAO HIROSHI (JP)
YAMASHITA KOKI (JP)
TAKEDA TOSHIHIRO (JP)
UEDA YASUYOSHI (JP)

Application Number:

PCT/JP2001/005440

Publication Date:

January 03, 2002

Filing Date:

June 26, 2001

Export Citation:

Click for automatic bibliography generation Help

Assignee:

KANEKA CORP (JP)
MURAO HIROSHI (JP)
YAMASHITA KOKI (JP)
TAKEDA TOSHIHIRO (JP)
UEDA YASUYOSHI (JP)

International Classes:

C07D263/24; C07B57/00; C07B61/00; C07C227/20; C07C227/32; C07C227/42; C07C229/34; C07D263/20; C07C229/22; (IPC1-7): C07C227/30; C07B53/00; C07C227/42; C07C229/22; C07D263/24

Foreign References:

US4294966A	1981-10-13
JPS322675B1	1957-05-01
JPS3621317B1	1961-11-06
EP0156279A2	1985-10-02
JPH06179641A	1994-06-28
EP0930292A1	1999-07-21
JPS5835152A	1983-03-01
JPS374310B1	1962-06-13
JPS6422849A	1989-01-25
EP0435068A2	1991-07-03
JPS321323B1	1957-02-23

Other References: