Title:
PROCESS FOR PRODUCING ANTIHERPESVIRUS PREPARATION FOR EXTERNAL USE
Document Type and Number:
WIPO Patent Application WO/2004/069261
Kind Code:
A1
Abstract:
A process for producing an antiherpesvirus preparation for external use which contains as an active ingredient a 5-[(E)-2-halogenovinyl]arabinofuranosyluracil represented by the following general formula (I), characterized in that in any one or more of steps for incorporating the active ingredient into a base, heating is conducted at a reduced pressure. In the formula (I), X represents halogeno. This process yields an external-use preparation which is an antiherpesvirus preparation having high antiherpesvirus activity and, despite this, is excellent in safety and stability.
Inventors:
YAMAMOTO MASAICHI (JP)
MACHIDA HARUHIKO (JP)
MACHIDA HARUHIKO (JP)
Application Number:
PCT/JP2003/001047
Publication Date:
August 19, 2004
Filing Date:
February 03, 2003
Export Citation:
Assignee:
ARIGEN INC (JP)
YAMAMOTO MASAICHI (JP)
MACHIDA HARUHIKO (JP)
YAMAMOTO MASAICHI (JP)
MACHIDA HARUHIKO (JP)
International Classes:
A61K31/7072; A61P31/22; C07H19/09; (IPC1-7): A61K31/7072; A61P31/22
Foreign References:
| JPH09143096A | 1997-06-03 |
Other References:
CHEMICAL ABSTRACTS, vol. 96, no. 62635, Columbus, Ohio, US; XP002903705
CHEMICAL ABSTRACTS, vol. 119, no. 173633, Columbus, Ohio, US; XP002903706
SADANOBU OKANO: "Shin.Yakuzaigaku Soron", 10 April 1987, NANKODO CO,LTD., pages: 88, XP002903707
CHEMICAL ABSTRACTS, vol. 119, no. 173633, Columbus, Ohio, US; XP002903706
SADANOBU OKANO: "Shin.Yakuzaigaku Soron", 10 April 1987, NANKODO CO,LTD., pages: 88, XP002903707
Attorney, Agent or Firm:
Hirose, Shoichi (4-2 Nihonbashi Honcho 4-chom, Chuo-ku Tokyo, JP)
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