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Title:
PROCESS FOR PRODUCING AZACYCLOALKANE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/1992/007827
Kind Code:
A1
Abstract:
A process for producing an azacycloalkane derivative represented by general formula (II), wherein m represents an integer of 1 to 3, n2 represents an integer of 2 to 10, and R represents C3 to C12 alkyl, which comprises reacting 1-(n-alkenyl)azacycloalkan-2-one represented by general formula (I) wherein, m is as defined above and n1 represents an integer of 0 to 8, with an alkyl mercaptan in the presence of a radical initiator in an organic solvent, treating the reaction product with a reducing agent in a watery organic solvent, followed by purification through distillation.

Inventors:
SAITA MASARU (JP)
INOUE HISATAKA (JP)
HACHIYA TERUMI (JP)
YAHIRO SHIGENORI (JP)
NODA KANJI (JP)
Application Number:
PCT/JP1991/001451
Publication Date:
May 14, 1992
Filing Date:
October 23, 1991
Export Citation:
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Assignee:
HISAMITSU PHARMACEUTICAL CO (JP)
International Classes:
C07D207/27; C07D211/76; C07D223/10; C07D227/087; C07D207/26; (IPC1-7): A61K47/22; C07D207/27; C07D211/76; C07D223/10
Foreign References:
JPS6330466A1988-02-09
JPS62238261A1987-10-19
JPS62238261A1987-10-19
Other References:
See also references of EP 0555483A4
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