PROCESS FOR PRODUCING CYCLIC COMPOUND

Title:

PROCESS FOR PRODUCING CYCLIC COMPOUND

Document Type and Number:

WIPO Patent Application WO/2003/080543

Kind Code:

A1

Abstract:

A process for producing a cyclic compound, i.e., a ß-lactam compound, represented by the following formula (3), which comprises the step of reacting a compound represented by the following formula (1) with 2 to 5 mol of a trialkyl phosphite represented by the formula (R⁵O)₃P (wherein R⁵ represents ethyl, etc.) per mol of that compound and the step of heating the resultant reaction mixture in a diluent, characterized by including before the heating step a step in which the trialkyl phosphite remaining unreacted is completely removed from the reaction mixture. (1) → (2) → (3) In the formulae, X represents sulfur, etc.; Y represents nitrogen, etc.; n is 0 or 1; R¹ represents optionally substituted C_1-10 alkyl, etc.; R² and R³ each represents an optionally substituted alkyl or heterocyclic group, etc.; R⁴ represents C_1-6 alkenyloxy, etc.; and R¹ and R² may be bonded to form a ß-lactam ring, etc.

Inventors:

KANEKO AKIRA (JP)

Application Number:

PCT/JP2003/003737

Publication Date:

October 02, 2003

Filing Date:

March 26, 2003

Export Citation:

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Assignee:

NIPPON SODA CO (JP)
SUNTORY LTD (JP)
KANEKO AKIRA (JP)

International Classes:

C07D403/12; C07D499/00; C07D499/04; C07D501/00; C07D501/02; C07D503/02; C07D505/02; (IPC1-7): C07B37/10; C07F7/18; C07D477/14; C07D487/04; C07D499/04; C07D503/02; C07D505/02; C07D501/02

Foreign References:

JPH0672875A	1994-03-15
EP0597401A2	1994-05-18
JPS6422880A	1989-01-25
EP0273747A1	1988-07-06
EP0212404A1	1987-03-04
JPS63162694A	1988-07-06
JPH0672875A	1994-03-15

Other References: