Title:
PROCESS OF PRODUCING ENVIRONMENTALLY SAFE TRANSGENIC ORGANISMS
Document Type and Number:
WIPO Patent Application WO2002096192
Kind Code:
A3
Abstract:
A process of producing a transgenic multi-cellular plant or animal organism expressing a trait of interest and having a controlled distribution of said trait to progeny, wherein said process comprises hybridising a first multi-cellular organism or a cell thereof having a first heterologous DNA sequence comprising a first fragment of a nucleotide sequence encoding said trait of interest and a second multi-cellular organism or a cell thereof having a second heterologous DNA sequence comprising a second fragment of the nucleotide sequence encoding said trait of interest, whereby said first and said second heterologous sequences are designed such that said trait of interest arises due to RNA trans-splicing after said hybridation.
Inventors:
WERNER STEFAN (DE)
MARILLONNET SYLVESTRE (DE)
KLIMYUK VICTOR (DE)
GLEBA YURI (DE)
MARILLONNET SYLVESTRE (DE)
KLIMYUK VICTOR (DE)
GLEBA YURI (DE)
Application Number:
PCT/EP2002/004724
Publication Date:
July 31, 2003
Filing Date:
April 29, 2002
Export Citation:
Assignee:
ICON GENETICS AG (DE)
WERNER STEFAN (DE)
MARILLONNET SYLVESTRE (DE)
KLIMYUK VICTOR (DE)
GLEBA YURI (DE)
WERNER STEFAN (DE)
MARILLONNET SYLVESTRE (DE)
KLIMYUK VICTOR (DE)
GLEBA YURI (DE)
International Classes:
A01H1/00; A01H5/00; A01K67/027; C12N15/09; C12N15/82; C12N15/85; (IPC1-7): C12N15/82; A01H5/00
Domestic Patent References:
| WO2000052146A2 | 2000-09-08 | |||
| WO2000071701A1 | 2000-11-30 | |||
| WO1992013090A1 | 1992-08-06 |
Other References:
AYRE BRIAN G ET AL: "Design of highly specific cytotoxins by using trans-splicing ribozymes.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 96, no. 7, 30 March 1999 (1999-03-30), March 30, 1999, pages 3507 - 3512, XP002227596, ISSN: 0027-8424
PUTTARAJU M ET AL: "Spliceosome-mediated RNA trans-splicing as a tool for gene therapy", NATURE BIOTECHNOLOGY, NATURE PUBLISHING, US, vol. 17, no. 3, March 1999 (1999-03-01), pages 246 - 252, XP002130564, ISSN: 1087-0156
PUTTARAJU M ET AL: "Spliceosome-mediated RNA trans-splicing as a tool for gene therapy", NATURE BIOTECHNOLOGY, NATURE PUBLISHING, US, vol. 17, no. 3, March 1999 (1999-03-01), pages 246 - 252, XP002130564, ISSN: 1087-0156
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