Title:
PROCESS FOR PRODUCING GROUP B SAPONIN
Document Type and Number:
WIPO Patent Application WO/2005/097815
Kind Code:
A1
Abstract:
A process for mass producing soyasaponin B being a raw material for therapeutic agent for hepatitis ME3738 (methyl derivative of soyasapogenol B) at low cost. There is provided a process for producing group B saponin, characterized by including the steps of: (1) adding a lower aliphatic alcohol or hydrated lower aliphatic alcohol to an extraction fraction of soyasaponins so as to generate deposit in acidic condition; (2) washing the deposit obtained in the previous step with a lower aliphatic alcohol or hydrated lower aliphatic alcohol and dissolving the washed deposit in a lower aliphatic alcohol; (3) concentrating the solution obtained in the previous step, adding water so as to generate deposit in acidic condition, and effecting adsorption of generated deposit on a carrier to thereby recover the same; and (4) washing the carrier obtained in the previous step with a fat-soluble solvent and conducting extraction with a lower aliphatic alcohol.
Inventors:
HASEGAWA TOSHIFUMI (JP)
KICHIKAWA EIICHI (JP)
KATO KIYOTAKA (JP)
TAKAGI SHIRO (JP)
KIMURA MASAAKI (JP)
KICHIKAWA EIICHI (JP)
KATO KIYOTAKA (JP)
TAKAGI SHIRO (JP)
KIMURA MASAAKI (JP)
Application Number:
PCT/JP2005/004174
Publication Date:
October 20, 2005
Filing Date:
March 10, 2005
Export Citation:
Assignee:
MEIJI SEIKA KAISHA (JP)
HASEGAWA TOSHIFUMI (JP)
KICHIKAWA EIICHI (JP)
KATO KIYOTAKA (JP)
TAKAGI SHIRO (JP)
KIMURA MASAAKI (JP)
HASEGAWA TOSHIFUMI (JP)
KICHIKAWA EIICHI (JP)
KATO KIYOTAKA (JP)
TAKAGI SHIRO (JP)
KIMURA MASAAKI (JP)
International Classes:
C07H15/256; (IPC1-7): C07H15/256
Foreign References:
| JPS6016999A | 1985-01-28 | |||
| JPS625917A | 1987-01-12 |
Attorney, Agent or Firm:
Kubota, Fujio (3-12 Nihombashi 3-chom, Chuo-ku Tokyo 27, JP)
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