PROCESS FOR PRODUCING HIGH-PURITY 1-BENZYL-3-AMINOPYRROLIDINE

WIPO Patent Application WO/2010/079605

A1

An industrially practicable purification method is provided by which 1-benzyl-3-aminopyrrolidine having a high chemical purity can be produced in a high yield. A salt is formed from tartaric acid and low-chemical-purity 1-benzyl-3-aminopyrrolidine containing impurities. The salt is crystallized from a mixed solvent comprising water and an organic solvent miscible with water to thereby produce high-purity 1-benzyl-3-aminopyrrolidine.

FUJINO, Toshihiro (Toray Fine Chemicals Co. Ltd., 9-1, Oe-cho, Minato-ku, Nagoya-sh, Aichi 02, 45585, JP)
藤野 年弘 (〒02 愛知県名古屋市港区大江町９番地の１ 東レ・ファインケミカル株式会社 スペシャルティ研究室内 Aichi, 45585, JP)
OGAWA, Ryuji (Toray Fine Chemicals Co. Ltd., 9-1, Oe-cho, Minato-ku, Nagoya-sh, Aichi 02, 45585, JP)

JP2009/050167

July 15, 2010

January 09, 2009

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TORAY FINE CHEMICALS CO., LTD. (8-1 Mihama 1-chome, Urayasu-shi Chiba, 55, 27985, JP)
東レ・ファインケミカル株式会社 (〒55 千葉県浦安市美浜１丁目８番１号 Chiba, 27985, JP)
FUJINO, Toshihiro (Toray Fine Chemicals Co. Ltd., 9-1, Oe-cho, Minato-ku, Nagoya-sh, Aichi 02, 45585, JP)
藤野 年弘 (〒02 愛知県名古屋市港区大江町９番地の１ 東レ・ファインケミカル株式会社 スペシャルティ研究室内 Aichi, 45585, JP)

C07D207/14; C07B63/00; C07D207/00; C07B63/00

IWAMI, Tomonori (TORAY INDUSTRIES INC.,1-1, Sonoyama 1-chome,Otsu-sh, Shiga 58, 52085, JP)

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