Title:
PROCESS FOR PRODUCING ICOSAPENTAENOIC ACID BY GENETIC RECOMBINATION
Document Type and Number:
WIPO Patent Application WO/1998/001565
Kind Code:
A1
Abstract:
An advantageous process for producing icosapentaenoic acid (EPA) useful as medicine, pesticide, food, feed and the like by obtaining a gene coding for a group of biosynthetases for EPA from a microorganism, preparing a plasmid by connecting the gene to a vector, transforming $i(Escherichia coli) by using the plasmid, and culturing the transformant.
Inventors:
YAZAWA KAZUNAGA
YAMADA AKIKO
KONDO KIYOSI
KATO SEISHI
YAMADA AKIKO
KONDO KIYOSI
KATO SEISHI
Application Number:
PCT/JP1997/002371
Publication Date:
January 15, 1998
Filing Date:
July 09, 1997
Export Citation:
Assignee:
SAGAMI CHEM RES (JP)
International Classes:
C12N1/21; C12N15/52; C12P7/64; (IPC1-7): C12N15/52; C12N1/21; C12P7/64
Foreign References:
| JPH0646864A | 1994-02-22 | |||
| JPH08242867A | 1996-09-24 | |||
| JPH0223877A | 1990-01-26 |
Other References:
LIPIDS, Vol. 31 (Suppl.), (Mar. 1996), K. YAZAWA, "Production of Eicosapentaenoic Acid from Marine Bacteria", p. S297-S300.
J. FERMENT. BIOENG., Vol. 75, (1993), S. ADACHI et al., "Acidolysis of Sardine Oil by Lipase to Concentration Eicosapentaenoic and Docosahexaenoic Acids in Glycerides", p. 259-264.
NIPPON SUISAN GAKKAISHI, Vol. 54(10), (1988), K. YAZAWA et al., "Eicosapentaenoic Acid Productivity of the Bacteria Isolated from Fish Intestines", p. 1835-1838.
See also references of EP 0913473A4
J. FERMENT. BIOENG., Vol. 75, (1993), S. ADACHI et al., "Acidolysis of Sardine Oil by Lipase to Concentration Eicosapentaenoic and Docosahexaenoic Acids in Glycerides", p. 259-264.
NIPPON SUISAN GAKKAISHI, Vol. 54(10), (1988), K. YAZAWA et al., "Eicosapentaenoic Acid Productivity of the Bacteria Isolated from Fish Intestines", p. 1835-1838.
See also references of EP 0913473A4
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