Title:
PROCESS FOR PRODUCING N-PROPANOL AND PROPIONIC ACID USING METABOLICALLY ENGINEERED PROPIONIBACTERIA
Document Type and Number:
WIPO Patent Application WO/2014/099707
Kind Code:
A3
Abstract:
A metabolically engineered propionibacteria, genomically modified to express a bifunctional aldehyde/alcohol dehydrogenase identified as GenBank Gene ID: 6062148; GI: 170080868, having activity on propionyl-CoA, is prepared and used in a fermentative process to biosynthetically prepare n-propanol, propionic acid, or a combination thereof.
Inventors:
YANG SHANG-TIAN (US)
AMMAR EHAB (US)
STOWERS CHRISTOPHER C (US)
RODRIGUEZ BRANDON A (US)
AMMAR EHAB (US)
STOWERS CHRISTOPHER C (US)
RODRIGUEZ BRANDON A (US)
Application Number:
PCT/US2013/075248
Publication Date:
September 25, 2014
Filing Date:
December 16, 2013
Export Citation:
Assignee:
DOW GLOBAL TECHNOLOGIES LLC (US)
UNIV OHIO STATE (US)
UNIV OHIO STATE (US)
International Classes:
C07K14/245; A23L19/00; C12P7/52; C12P7/04
Domestic Patent References:
| WO2011029166A1 | 2011-03-17 | |||
| WO2012067510A1 | 2012-05-24 |
Other References:
ATTEIA ARIANE ET AL: "Bifunctional aldehyde/alcohol dehydrogenase (ADHE) in chlorophyte algal mitochondria.", PLANT MOLECULAR BIOLOGY SEP 2003, vol. 53, no. 1-2, September 2003 (2003-09-01), pages 175 - 188, XP002724185, ISSN: 0167-4412
AMMAR EHAB MOHAMED ET AL: "Metabolic engineering of Propionibacterium freudenreichii for n-propanol production", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 97, no. 10, May 2013 (2013-05-01), pages 4677 - 4690, XP002724186
AMMAR EHAB MOHAMED ET AL: "Metabolic engineering of Propionibacterium freudenreichii for n-propanol production", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, vol. 97, no. 10, May 2013 (2013-05-01), pages 4677 - 4690, XP002724186
Attorney, Agent or Firm:
HOWARD, Dan (P.O. Box 1967Midland, Michigan, US)
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