Title:
PROCESS FOR PRODUCING POLYAMINES COMPRISING THE ENZYMATIC OXIDATION OF AMINO ALCOHOLS
Document Type and Number:
WIPO Patent Application WO/2011/051433
Kind Code:
A3
Abstract:
The present invention relates to a process for the production of a polyamine involving the use of enzymes; in particular to a process performed in aqueous environment; to the polyamines produced by said method; as well as the use of said polyamines for manufacturing paper, for immobilizing enzymes, or for preparing pharmaceutical or cosmetical compositions. The invention also relates to a novel method for in situ regeneration of cofactors NAD(P)+.
Inventors:
HAUER BERNHARD (DE)
ENGELMARK CASSIMJEE DAVID KARIM (SE)
BERGLUND PER (SE)
ENGELMARK CASSIMJEE DAVID KARIM (SE)
BERGLUND PER (SE)
Application Number:
PCT/EP2010/066449
Publication Date:
September 07, 2012
Filing Date:
October 29, 2010
Export Citation:
Assignee:
BASF SE (DE)
HAUER BERNHARD (DE)
ENGELMARK CASSIMJEE DAVID KARIM (SE)
BERGLUND PER (SE)
HAUER BERNHARD (DE)
ENGELMARK CASSIMJEE DAVID KARIM (SE)
BERGLUND PER (SE)
International Classes:
C12P13/00; C08G73/02
Foreign References:
| US20080069969A1 | 2008-03-20 | |||
| US4048148A | 1977-09-13 | |||
| EP1364641A1 | 2003-11-26 |
Other References:
PATEL, R.N. ET AL.: "Microbial Oxidation of Methanol: Properties of Crystallized Alcohol Oxidase from a Yeast, Pichia sp.", ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, vol. 210, no. 2, 1981, pages 481 - 488, XP024757517
ANDERSSON, L. & WOLFENDEN, R.: "A General Method of alpha-Aminoaldehyde Synthesis Using Alcohol Dehydrogenase", ANALYTICAL BIOCHEMISTRY, vol. 124, no. 1, 15 July 1982 (1982-07-15), pages 150 - 157, XP024826254
MATOS J.R. ET AL.: "Enantioselectivity of Alcohol Dehydrogenase-Catalyzed Oxidation of 1,2-Diols and Aminoalcohols", BIOORGANIC CHEMISTRY, vol. 13, no. 2, 1985, pages 121 - 130, XP024022165
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE; 1958, INGBERMAN, A.K. & WALTON, R.K.: "Low toxicity aliphatic amines as crosslinking agents for polyepoxy resins", XP002660148, Database accession no. 1961:7629
KAUR, N. ET AL.: "Designing the Polyamine Pharmacophore: Influence of N-Substituents on the Transport Behavior of Polyamine Conjugates", JOURNAL OF MEDICINAL CHEMISTRY, vol. 51, no. 8, 2008, pages 2551 - 2560, XP002660149
RIEBEL, B.R. ET AL.: "Cofactor Regeneration of both NAD+ from NADH and NADP+ from NADPH:NADH Oxidase from Lactobacillus sanfranciscensis", ADVANCED SYNTHESIS & CATALYSIS, vol. 345, no. 6-7, 3 June 2003 (2003-06-03), pages 707 - 712, XP002660150
ANDERSSON, L. & WOLFENDEN, R.: "A General Method of alpha-Aminoaldehyde Synthesis Using Alcohol Dehydrogenase", ANALYTICAL BIOCHEMISTRY, vol. 124, no. 1, 15 July 1982 (1982-07-15), pages 150 - 157, XP024826254
MATOS J.R. ET AL.: "Enantioselectivity of Alcohol Dehydrogenase-Catalyzed Oxidation of 1,2-Diols and Aminoalcohols", BIOORGANIC CHEMISTRY, vol. 13, no. 2, 1985, pages 121 - 130, XP024022165
DATABASE CAPLUS [online] CHEMICAL ABSTRACTS SERVICE; 1958, INGBERMAN, A.K. & WALTON, R.K.: "Low toxicity aliphatic amines as crosslinking agents for polyepoxy resins", XP002660148, Database accession no. 1961:7629
KAUR, N. ET AL.: "Designing the Polyamine Pharmacophore: Influence of N-Substituents on the Transport Behavior of Polyamine Conjugates", JOURNAL OF MEDICINAL CHEMISTRY, vol. 51, no. 8, 2008, pages 2551 - 2560, XP002660149
RIEBEL, B.R. ET AL.: "Cofactor Regeneration of both NAD+ from NADH and NADP+ from NADPH:NADH Oxidase from Lactobacillus sanfranciscensis", ADVANCED SYNTHESIS & CATALYSIS, vol. 345, no. 6-7, 3 June 2003 (2003-06-03), pages 707 - 712, XP002660150
Attorney, Agent or Firm:
PATENTANWÄLTE REITSTÖTTER KINZEBACH (München, DE)
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