Title:
PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE β-PHENYLALANINE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2003/068727
Kind Code:
A1
Abstract:
A process which comprises reacting an N-acyl-β- phenylalanine derivative with a specific reagent for optical resolution to form diastereomeric salts, subjecting the diastereomeric salts to optical resolution, removing the reagent from each of the resolved diastereomeric salts to obtain an optically active N-acyl-β-phenylalanine derivative, and deacylating this derivative into an optically active β-phenylalanine derivative. According to the process, optically active N-acyl-β-phenylalanine derivatives and optically active β-phenylalanine derivatives can be produced with industrial advantage.
Inventors:
NOHIRA HIROYUKI (JP)
Application Number:
PCT/JP2003/001363
Publication Date:
August 21, 2003
Filing Date:
February 10, 2003
Export Citation:
Assignee:
AJINOMOTO KK (JP)
NOHIRA HIROYUKI (JP)
NOHIRA HIROYUKI (JP)
International Classes:
C07B57/00; C07C211/27; C07C215/30; C07C227/34; C07C229/34; C07C231/20; C07C233/47; (IPC1-7): C07C231/20; C07C227/20; C07C229/34; C07C233/47
Foreign References:
| EP1013769A1 | 2000-06-28 | |||
| JPS62123156A | 1987-06-04 |
Other References:
See also references of EP 1484314A4
Attorney, Agent or Firm:
Shimokoshi, Masao (Taka-ai Bldg. 15-2, Nihombashi 3-chom, Chuo-ku Tokyo, JP)
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