Title:
PROCESS FOR PRODUCTION OF STEROID COMPOUND
Document Type and Number:
WIPO Patent Application WO/2007/049672
Kind Code:
A1
Abstract:
Disclosed is a process for production of a steroid compound having a partial structure represented by the formula (2) by oxidizing a steroid compound having a partial structure represented by the formula (1), without the need of using any specialized apparatus, in a safe and economically advantageous manner, with less environmental load, in a simple manner and with high efficiency. Specifically, disclosed is a process for production of a steroid compound having a partial structure in each of ring A and ring B of the steroid skeleton represented by the formula (2), comprising reacting a steroid compound having a partial structure in each of ring A and ring B of the steroid skeleton represented by the formula (1) with a catalytic amount of a copper halide in the presence of an oxygen. wherein R represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms. wherein R is as defined in the formula (1) above.
Inventors:
TATSUTA KUNIAKI (JP)
MARUHASHI KAZUO (JP)
YANO SHINGO (JP)
MARUHASHI KAZUO (JP)
YANO SHINGO (JP)
Application Number:
PCT/JP2006/321330
Publication Date:
May 03, 2007
Filing Date:
October 26, 2006
Export Citation:
Assignee:
TAIHO PHARMACEUTICAL CO LTD (JP)
TATSUTA KUNIAKI (JP)
MARUHASHI KAZUO (JP)
YANO SHINGO (JP)
TATSUTA KUNIAKI (JP)
MARUHASHI KAZUO (JP)
YANO SHINGO (JP)
International Classes:
C07J1/00
Foreign References:
| JP2001525855A | 2001-12-11 | |||
| US20050090477A1 | 2005-04-28 | |||
| US20050090477A1 | 2005-04-28 | |||
| JP2001525855A | 2001-12-11 |
Other References:
HELMUT G. ET AL: "Preparation of 3-ketodesogestrel metabolites by microbial transformation and chemical synthesis", STEROIDS, vol. 62, no. 5, 1997, pages 437 - 443, XP003011934
PEMMARAJU N.R. ET AL: "Preparative chemical methods for aromatization of 19-nor-delta4-3-oxosteroids", STEROIDS, vol. 59, no. 11, 1994, pages 621 - 627, XP003011935
See also references of EP 1947107A4
PEMMARAJU N.R. ET AL: "Preparative chemical methods for aromatization of 19-nor-delta4-3-oxosteroids", STEROIDS, vol. 59, no. 11, 1994, pages 621 - 627, XP003011935
See also references of EP 1947107A4
Attorney, Agent or Firm:
SAEGUSA, Eiji et al. (1-7-1 Doshomachi, Chuo-k, Osaka-shi Osaka 45, JP)
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