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Title:
A PROCESS FOR THE RESOLUTION OF NEFOPAM
Document Type and Number:
WIPO Patent Application WO2005056539
Kind Code:
A3
Abstract:
A process for increasing the optical purity of a mixture of enantiomers of nefopam uses a substantially single enantiomer of a O,O-diaroyltartaric acid as a resolving agent, via a bisnefopam salt of the acid. This salt is new.

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Inventors:
HARRIS MICHAEL JOHN (GB)
BROWN STUART (GB)
Application Number:
PCT/GB2004/005198
Publication Date:
November 24, 2005
Filing Date:
December 13, 2004
Export Citation:
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Assignee:
ARAKIS LTD (GB)
HARRIS MICHAEL JOHN (GB)
BROWN STUART (GB)
International Classes:
C07D267/22; (IPC1-7): C07D267/00
Foreign References:
EP0970935A12000-01-12
Other References:
BLASCHKE, G.; ET AL., ARCH. PHARM., vol. 320, 1987, pages 341 - 347, XP008046821
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