Title:
PROCESS FOR SURFACE MODIFYING SUBSTRATES AND MODIFIED SUBSTRATES RESULTING THEREFROM
Document Type and Number:
WIPO Patent Application WO2002016974
Kind Code:
A3
Abstract:
The invention relates to a process for coating a material surface, comprising the steps of: (a) applying to the material surface a tie layer comprising a polyionic material; (b) covalently binding a bifunctional compound comprising an ethylenically unsaturated double bond to the tie layer; and (c) graft polymerizing a hydrophilic monomer onto the compound comprising the ethylenically unsaturated double bond. The coated articles that are obtainable by the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.
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Inventors:
QIU YONGXING (US)
WINTERTON LYNN COOK (US)
LALLY JOHN MARTIN (US)
CHABRECEK PETER (CH)
PASIC PAUL (AU)
GRIESSER HANS JOERG (AU)
KAMBOURIS PETER (AU)
WINTERTON LYNN COOK (US)
LALLY JOHN MARTIN (US)
CHABRECEK PETER (CH)
PASIC PAUL (AU)
GRIESSER HANS JOERG (AU)
KAMBOURIS PETER (AU)
Application Number:
PCT/EP2001/009712
Publication Date:
July 18, 2002
Filing Date:
August 22, 2001
Export Citation:
Assignee:
NOVARTIS AG (CH)
NOVARTIS ERFIND VERWALT GMBH (AT)
COMMW SCIENT IND RES ORG (AU)
QIU YONGXING (US)
WINTERTON LYNN COOK (US)
LALLY JOHN MARTIN (US)
CHABRECEK PETER (CH)
PASIC PAUL (AU)
GRIESSER HANS JOERG (AU)
KAMBOURIS PETER (AU)
NOVARTIS ERFIND VERWALT GMBH (AT)
COMMW SCIENT IND RES ORG (AU)
QIU YONGXING (US)
WINTERTON LYNN COOK (US)
LALLY JOHN MARTIN (US)
CHABRECEK PETER (CH)
PASIC PAUL (AU)
GRIESSER HANS JOERG (AU)
KAMBOURIS PETER (AU)
International Classes:
A61L27/34; C08J7/04; C08J7/16; G02B1/04; G02B1/14; G02C7/04; (IPC1-7): G02B1/04; A61L27/34; G02B1/10; C08J7/04; C08J7/16
Domestic Patent References:
| WO1999057581A1 | 1999-11-11 | |||
| WO1998005269A1 | 1998-02-12 |
Foreign References:
| US5807636A | 1998-09-15 | |||
| EP0989418A2 | 2000-03-29 |
Other References:
See also references of EP 1315985A2
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