PROCESS - PLIVA ISTRAZIVANJE I RAZVOJ D

Title:

PROCESS

Document Type and Number:

WIPO Patent Application WO2006008562

Kind Code:

A8

Abstract:

The present disclosure relates to an improved process for the preparation of enantiomerically enriched alcohols of Formula (I), from the corresponding ketone of Formula (II), by asymmetric transfer hydrogenation, using a hydrogen donor, catalyzed by a ruthenium or rhodium complex of an optically active N-sulfamoyl-1,2-diamine. R is as defined herein.

Inventors:

AVDAGIC AMIR (HR)
MOHAR BARBARA (SI)
STERK DAMJAN (SI)
STEPHAN MICHEL (FR)

Application Number:

PCT/HR2005/000040

Publication Date:

April 27, 2006

Filing Date:

July 21, 2005

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Assignee:

PLIVA ISTRAZIVANJE I RAZVOJ D (HR)
AVDAGIC AMIR (HR)
MOHAR BARBARA (SI)
STERK DAMJAN (SI)
STEPHAN MICHEL (FR)

International Classes:

C07D215/14

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