Title:
PROCESSES FOR THE PREPARATION OF DEHYDROEPIANDROSTERONE AND ITS INTERMEDIATES
Document Type and Number:
WIPO Patent Application WO/2014/188353
Kind Code:
A3
Abstract:
The present application relates to a regioselective and stereoselective processes for the preparation of dehydroepiandrosterone (DHEA) and processes for its intermediates.
Inventors:
FRYSZKOWSKA ANNA (GB)
QUIRMBACH MICHAEL SIEGFRIED (CH)
GORANTLA SRIKANTH SARAT CHANDRA (IN)
ALIETI SANJAY REDDY (IN)
POREDDY SRINIVAS REDDY (IN)
DINNE NARESH KUMAR REDDY (IN)
TIMMANNA UPADHYA (IN)
DAHANUKAR VILAS (IN)
QUIRMBACH MICHAEL SIEGFRIED (CH)
GORANTLA SRIKANTH SARAT CHANDRA (IN)
ALIETI SANJAY REDDY (IN)
POREDDY SRINIVAS REDDY (IN)
DINNE NARESH KUMAR REDDY (IN)
TIMMANNA UPADHYA (IN)
DAHANUKAR VILAS (IN)
Application Number:
PCT/IB2014/061590
Publication Date:
April 02, 2015
Filing Date:
May 21, 2014
Export Citation:
Assignee:
REDDYS LAB LTD DR (IN)
International Classes:
C07J75/00; C07J1/00; C12P33/16
Foreign References:
| US8227208B2 | 2012-07-24 | |||
| EP0133995A2 | 1985-03-13 | |||
| US5604213A | 1997-02-18 | |||
| US6284750B1 | 2001-09-04 |
Other References:
BAWA ET AL.: "Enzymatic Reduction of Ketones to Optically Active Secondary Alcohols", JOURNAL OF PHYSICAL SCIENCE, vol. 19, no. ISSUE, 2008, pages 1 - 5, XP055296669
JONES ET AL.: "Steroids and steroidases.VI. On the C-17 specificity of the 5-3-ketoisomerase of Pseudomonas testosterone and evidence for substrate micelle formation", CANADIAN JOURNAL OF CHEMISTRY, vol. 46, no. 9, 1968, pages 1459 - 1465, XP055296672
DANIEL L. PURICH ET AL.: "The Enzyme Reference: A Comprehensive Guidebook to Enzyme Nomenclature, Reactions, and Methods", December 2002 (2002-12-01), pages 782 AND 783, XP008182555
AGUS ET AL.: "Aldo-keto Reductase Family 1 Member C3 (AKR1C3) Is a Biomarker and Therapeutic Target for Castration-Resistant Prostate Cancer", MOLECULAR MEDICINE, vol. 18, 22 January 2013 (2013-01-22), pages 1449 - 1455, XP055296681
DATABASE GENBANK [online] 28 January 2014 (2014-01-28), COPELAND ET AL.: "SPHINGOMONAS WITTICHII RW1, COMPLETE GENOME", XP003032425, retrieved from NCBI Database accession no. CP000699
JONES ET AL.: "Steroids and steroidases.VI. On the C-17 specificity of the 5-3-ketoisomerase of Pseudomonas testosterone and evidence for substrate micelle formation", CANADIAN JOURNAL OF CHEMISTRY, vol. 46, no. 9, 1968, pages 1459 - 1465, XP055296672
DANIEL L. PURICH ET AL.: "The Enzyme Reference: A Comprehensive Guidebook to Enzyme Nomenclature, Reactions, and Methods", December 2002 (2002-12-01), pages 782 AND 783, XP008182555
AGUS ET AL.: "Aldo-keto Reductase Family 1 Member C3 (AKR1C3) Is a Biomarker and Therapeutic Target for Castration-Resistant Prostate Cancer", MOLECULAR MEDICINE, vol. 18, 22 January 2013 (2013-01-22), pages 1449 - 1455, XP055296681
DATABASE GENBANK [online] 28 January 2014 (2014-01-28), COPELAND ET AL.: "SPHINGOMONAS WITTICHII RW1, COMPLETE GENOME", XP003032425, retrieved from NCBI Database accession no. CP000699
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