Title:
PRODRUGS OF (2R)-2-PROPYLOCTANOIC ACID FOR TREATMENT OF STROKE
Document Type and Number:
WIPO Patent Application WO2006055381
Kind Code:
A3
Abstract:
Disclosed are prodrugs of (2R)-2-propyloctanoic acid, and pharmaceutical compositions comprising them, which may be effective in modulating multiple events in the biochemical cascade of stroke. Also disclosed are methods of treating patients who have had a stroke, or are at risk of stroke, by administering the compounds or compositions of the invention.
Inventors:
MUNOZ BENITO (US)
PAYNE JOSEPH E (US)
PRASIT PETPIBOON (US)
REGER THOMAS S (US)
SMITH NICHOLAS D (US)
PAYNE JOSEPH E (US)
PRASIT PETPIBOON (US)
REGER THOMAS S (US)
SMITH NICHOLAS D (US)
Application Number:
PCT/US2005/040727
Publication Date:
August 03, 2006
Filing Date:
November 10, 2005
Export Citation:
Assignee:
MERCK & CO INC (US)
MUNOZ BENITO (US)
PAYNE JOSEPH E (US)
PRASIT PETPIBOON (US)
REGER THOMAS S (US)
SMITH NICHOLAS D (US)
MUNOZ BENITO (US)
PAYNE JOSEPH E (US)
PRASIT PETPIBOON (US)
REGER THOMAS S (US)
SMITH NICHOLAS D (US)
International Classes:
C07C69/02; C07C317/00; C07D243/08; C07D311/80
Foreign References:
JP2006016318A | 2006-01-19 |
Other References:
See also references of EP 1814838A4
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