Title:
PRODUCER CELL, METHOD FOR PRODUCING PRODUCER CELL, AND METHOD FOR PRODUCING ADENO-ASSOCIATED VIRUS
Document Type and Number:
WIPO Patent Application WO/2023/171698
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a producer cell for the production of an adeno-associated virus (AAV) wherein cell damage is avoided or suppressed at the establishment of a cell line, a method for producing the producer cell, and a method for producing an AAV using the producer cell. The present invention provides a producer cell that has a Cap gene under the control of a foreign promoter and a Rep gene under the control of a foreign promoter in the chromosome, that is free from a VA-RNA gene and/or an E4 gene, and that is a mammalian cell.
Inventors:
MURAGUCHI TAICHI (JP)
MORI YUSUKE (JP)
UMETANI SAYAKO (JP)
MORI YUSUKE (JP)
UMETANI SAYAKO (JP)
Application Number:
PCT/JP2023/008736
Publication Date:
September 14, 2023
Filing Date:
March 08, 2023
Export Citation:
Assignee:
FUJIFILM CORP (JP)
International Classes:
C12N7/01; C12N5/10; C12N15/35; C12N15/864
Foreign References:
| JP2020536505A | 2020-12-17 | |||
| JP2022505095A | 2022-01-14 | |||
| JP2022516004A | 2022-02-24 |
Attorney, Agent or Firm:
SIKS & CO. (JP)
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