Title:
PRODUCT FOR EVALUATING RECURRENCE RISK OF LUNG CANCER PATIENT
Document Type and Number:
WIPO Patent Application WO/2023/231280
Kind Code:
A1
Abstract:
Disclosed in the present invention is the use of a reagent for detecting markers in preparation of a product for evaluating the recurrence risk of lung cancer patients. A first aspect of the present application provides the use of the reagent for detecting markers in preparation of the product for evaluating the recurrence risk of lung cancer patients. Different models concerning the recurrence risk are established for lung cancer patients receiving adjuvant chemotherapy and not receiving adjuvant chemotherapy, different adjuvant treatment means for the lung cancer patients are distinguished, the recurrence risk of the patients is predicted by means of two sets of markers, and thus a proper adjuvant treatment means can be selected therefrom. For patients having a recurrence risk of receiving adjuvant chemotherapy higher than a recurrence risk of not receiving adjuvant chemotherapy, other treatment schemes in addition to adjuvant chemotherapy are preferentially; whereas adjuvant chemotherapy is preferred for patients having a higher recurrence risk of not receiving adjuvant chemotherapy.
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Inventors:
RAO AIBING (CN)
Application Number:
PCT/CN2022/127455
Publication Date:
December 07, 2023
Filing Date:
October 25, 2022
Export Citation:
Assignee:
SHENZHEN LUWEI BIOTECH BIOMANIFOLD TECH COMPANY LIMITED (CN)
International Classes:
C12Q1/6886; G16B40/00
Domestic Patent References:
| WO2013151677A1 | 2013-10-10 |
Foreign References:
| CN109735619A | 2019-05-10 | |||
| CN111394456A | 2020-07-10 | |||
| CN114622015A | 2022-06-14 | |||
| CN114934117A | 2022-08-23 |
Other References:
LU, YAN ET AL.: "Gene-Expression Signature Predicts Postoperative Recurrence in Stage I Non-Small Cell Lung Cancer Patients", PLOS ONE., vol. 7, no. 1, 23 January 2012 (2012-01-23), XP055177681, DOI: 10.1371/journal.pone.0030880
HUI WANG, XIANG MING; DING BOYING: "Relationship between a Disintegrin and Metalloproteinase and Tumors", CHINESE JOURNAL OF CLINICAL MEDICINE, vol. 20, no. 6, 25 December 2013 (2013-12-25), pages 864 - 867, XP093116904
YU-JUAN HUANG: "Study trend of the treatment of non-small-cell lung cancer with brain metastasis", CHONGQING MEDICAL JOURNAL, vol. 8, 30 August 2015 (2015-08-30), pages 1177 - 1179, XP093116906
HUI WANG, XIANG MING; DING BOYING: "Relationship between a Disintegrin and Metalloproteinase and Tumors", CHINESE JOURNAL OF CLINICAL MEDICINE, vol. 20, no. 6, 25 December 2013 (2013-12-25), pages 864 - 867, XP093116904
YU-JUAN HUANG: "Study trend of the treatment of non-small-cell lung cancer with brain metastasis", CHONGQING MEDICAL JOURNAL, vol. 8, 30 August 2015 (2015-08-30), pages 1177 - 1179, XP093116906
Attorney, Agent or Firm:
JIAQUAN IP LAW (CN)
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