Title:
PRODUCTION OF COMPOUNDS FROM PLANTS
Document Type and Number:
WIPO Patent Application WO/2010/040990
Kind Code:
A3
Abstract:
The invention provides a method for producing a molecule from roots of a plant, comprising applying a plant hormone to the roots that increases rhizosecretion of the molecule from the roots, and recovering the molecule. The plant hormone is typically an auxin, the secreted molecule is typically a recombinant protein, and the plant is typically grown in hydroponic culture.
More Like This:
Inventors:
DRAKE PASCAL MARK WAIN (GB)
DE MORAES MADEIRA LUISA (GB)
DE MORAES MADEIRA LUISA (GB)
Application Number:
PCT/GB2009/002370
Publication Date:
November 04, 2010
Filing Date:
October 06, 2009
Export Citation:
Assignee:
ST GEORGES HOSP MEDICAL SCHOOL (GB)
DRAKE PASCAL MARK WAIN (GB)
DE MORAES MADEIRA LUISA (GB)
DRAKE PASCAL MARK WAIN (GB)
DE MORAES MADEIRA LUISA (GB)
International Classes:
A01H3/04; A01G31/00; A01H4/00; A01H5/06
Domestic Patent References:
| WO2001061022A1 | 2001-08-23 | |||
| WO2007088024A1 | 2007-08-09 | |||
| WO1998049267A1 | 1998-11-05 |
Other References:
KNEER RALF ET AL: "Characterization of the elicitor-induced biosynthesis and secretion of genistein from roots of Lupinus luteus L", October 1999, JOURNAL OF EXPERIMENTAL BOTANY, VOL. 50, NR. 339, PAGE(S) 1553-1559, ISSN: 0022-0957, XP002577521
LOPEZ MARTHA L ET AL: "Enhancement of lead uptake by alfalfa (Medicago sativa) using EDTA and a plant growth promotor", October 2005, CHEMOSPHERE, VOL. 61, NR. 4, PAGE(S) 595-598, ISSN: 0045-6535, XP005098112
LOPEZ MARTHA L ET AL: "Gibberellic acid, kinetin, and the mixture indole-3-acetic acid-kinetin assisted with EDTA-induced lead hyperaccumulation in alfalfa plants", December 2007, ENVIRONMENTAL SCIENCE & TECHNOLOGY, VOL. 41, NR. 23, PAGE(S) 8165-8170, ISSN: 0013-936X, XP002577839
NAIDU V S G R ET AL: "Effect of synthetic auxins and Azorhizobium caulinodans on growth and yield of rice", 1 September 2004, INDIAN JOURNAL OF MICROBIOLOGY, HISAR, IN, PAGE(S) 211 - 213, ISSN: 0046-8991, XP005098112
YASER HAMMAD ET AL: "A possible role for phenyl acetic acid (PAA) on Alnus glutinosa nodulation by Frankia", 1 July 2003, PLANT AND SOIL ; AN INTERNATIONAL JOURNAL ON PLANT-SOIL RELATIONSHIPS, KLUWER ACADEMIC PUBLISHERS, DO, PAGE(S) 193 - 205, ISSN: 1573-5036, XP019293070
GROSSMANN KLAUS ET AL: "The mechanism of quinclorac selectivity in grasses", February 2000, PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, VOL. 66, NR. 2, PAGE(S) 83-91, ISSN: 0048-3575, XP002577840
ARTECA JEANNETTE M ET AL: "Brassinosteroid-induced exaggerated growth in hydroponically grown Arabidopsis plants", May 2001, PHYSIOLOGIA PLANTARUM, VOL. 112, NR. 1, PAGE(S) 104-112, ISSN: 0031-9317, XP002577841
LI ZHANHAI ET AL: "Effects of benzyladenine and naphthalene acetic acid on growth and camptothecin accumulation in Camptotheca acuminata seedlings.", September 2003, JOURNAL OF PLANT GROWTH REGULATION, VOL. 22, NR. 3, PAGE(S) 205-216, ISSN: 0721-7595, XP002577842
DEWIR Y H ET AL: "A simple method for mass propagation of Spathiphyllum cannifolium using an airlift bioreactor", May 2006, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY PLANT, VOL. 42, NR. 3, PAGE(S) 291-297, ISSN: 1054-5476, XP002577843
FEI HOUMAN ET AL: "Involvement of cytokinin in the stimulation of nodulation by low concentrations of ammonium in Pisum sativum", 1 July 2003, PHYSIOLOGIA PLANTARUM, MUNKSGAARD INTERNATIONAL PUBLISHERS, COPENHAGEN, DK LNKD- DOI:10.1034/J.1399-3054.2003.00123.X, PAGE(S) 447 - 455, ISSN: 0031-9317, XP009131491
NIRWAN R S ET AL: "High frequency shoot organogenesis in Sorghum bicolor (L) Moench", 1 July 2004, JOURNAL OF PLANT BIOCHEMISTRY AND BIOTECHNOLOGY, SOCIETY FOR PLANT BIOCHEMISTRY AND BIOTECHNOLOGY, NEW DEHLI, IN, PAGE(S) 145,149 - 152, ISSN: 0971-7811, XP009131608
CSABA G ET AL: "EFFECTS OF INSULIN TRI IODO THYRONINE AND SEROTONIN ON PLANT SEED DEVELOPMENT", 1982, PROTOPLASMA, VOL. 110, NR. 1, PAGE(S) 20-22, ISSN: 0033-183X, XP009131606
HINCHEE M A W ET AL: "THE CONTROL OF LATERAL ROOT DEVELOPMENT IN CULTURED PEA SEEDLINGS II. ROOT FASCIATION INDUCED BY AUXIN INHIBITORS", 1 January 1992, BOTANICA ACTA, STUTTGART, DE, PAGE(S) 121 - 126, ISSN: 0932-8629, XP009131587
HEUPEL THORSTEN ET AL: "The auxin antagonist p-chlorophenoxyisobutyric acid abolishes polar distribution of DNA synthesizing cells within the Meristem of Riella helicophylla", 1 January 1995, JOURNAL OF PLANT PHYSIOLOGY, FISCHER, STUTTGART, DE, PAGE(S) 757 - 759, ISSN: 0176-1617, XP009131591
MURASHIGE T AND SKOOG F: "A revised medium for rapid growth and bio assays with Tobacco tissue cultures", PHYSIOLOGIA PLANTARUM, vol. 15, 1962, pages 473 - 497, XP002577845
DRAKE PASCAL M W ET AL: "Rhizosecretion of a monoclonal antibody protein complex from transgenic tobacco roots.", May 2003, PLANT MOLECULAR BIOLOGY, VOL. 52, NR. 1, PAGE(S) 233-241, ISSN: 0167-4412, XP002577846
DRAKE PASCAL M W ET AL: "Development of rhizosecretion as a production system for recombinant proteins from hydroponic cultivated tobacco", October 2009, FASEB JOURNAL, VOL. 23, NR. 10, PAGE(S) 3581-3589, ISSN: 0892-6638, XP002577522
LOPEZ MARTHA L ET AL: "Enhancement of lead uptake by alfalfa (Medicago sativa) using EDTA and a plant growth promotor", October 2005, CHEMOSPHERE, VOL. 61, NR. 4, PAGE(S) 595-598, ISSN: 0045-6535, XP005098112
LOPEZ MARTHA L ET AL: "Gibberellic acid, kinetin, and the mixture indole-3-acetic acid-kinetin assisted with EDTA-induced lead hyperaccumulation in alfalfa plants", December 2007, ENVIRONMENTAL SCIENCE & TECHNOLOGY, VOL. 41, NR. 23, PAGE(S) 8165-8170, ISSN: 0013-936X, XP002577839
NAIDU V S G R ET AL: "Effect of synthetic auxins and Azorhizobium caulinodans on growth and yield of rice", 1 September 2004, INDIAN JOURNAL OF MICROBIOLOGY, HISAR, IN, PAGE(S) 211 - 213, ISSN: 0046-8991, XP005098112
YASER HAMMAD ET AL: "A possible role for phenyl acetic acid (PAA) on Alnus glutinosa nodulation by Frankia", 1 July 2003, PLANT AND SOIL ; AN INTERNATIONAL JOURNAL ON PLANT-SOIL RELATIONSHIPS, KLUWER ACADEMIC PUBLISHERS, DO, PAGE(S) 193 - 205, ISSN: 1573-5036, XP019293070
GROSSMANN KLAUS ET AL: "The mechanism of quinclorac selectivity in grasses", February 2000, PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, VOL. 66, NR. 2, PAGE(S) 83-91, ISSN: 0048-3575, XP002577840
ARTECA JEANNETTE M ET AL: "Brassinosteroid-induced exaggerated growth in hydroponically grown Arabidopsis plants", May 2001, PHYSIOLOGIA PLANTARUM, VOL. 112, NR. 1, PAGE(S) 104-112, ISSN: 0031-9317, XP002577841
LI ZHANHAI ET AL: "Effects of benzyladenine and naphthalene acetic acid on growth and camptothecin accumulation in Camptotheca acuminata seedlings.", September 2003, JOURNAL OF PLANT GROWTH REGULATION, VOL. 22, NR. 3, PAGE(S) 205-216, ISSN: 0721-7595, XP002577842
DEWIR Y H ET AL: "A simple method for mass propagation of Spathiphyllum cannifolium using an airlift bioreactor", May 2006, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY PLANT, VOL. 42, NR. 3, PAGE(S) 291-297, ISSN: 1054-5476, XP002577843
FEI HOUMAN ET AL: "Involvement of cytokinin in the stimulation of nodulation by low concentrations of ammonium in Pisum sativum", 1 July 2003, PHYSIOLOGIA PLANTARUM, MUNKSGAARD INTERNATIONAL PUBLISHERS, COPENHAGEN, DK LNKD- DOI:10.1034/J.1399-3054.2003.00123.X, PAGE(S) 447 - 455, ISSN: 0031-9317, XP009131491
NIRWAN R S ET AL: "High frequency shoot organogenesis in Sorghum bicolor (L) Moench", 1 July 2004, JOURNAL OF PLANT BIOCHEMISTRY AND BIOTECHNOLOGY, SOCIETY FOR PLANT BIOCHEMISTRY AND BIOTECHNOLOGY, NEW DEHLI, IN, PAGE(S) 145,149 - 152, ISSN: 0971-7811, XP009131608
CSABA G ET AL: "EFFECTS OF INSULIN TRI IODO THYRONINE AND SEROTONIN ON PLANT SEED DEVELOPMENT", 1982, PROTOPLASMA, VOL. 110, NR. 1, PAGE(S) 20-22, ISSN: 0033-183X, XP009131606
HINCHEE M A W ET AL: "THE CONTROL OF LATERAL ROOT DEVELOPMENT IN CULTURED PEA SEEDLINGS II. ROOT FASCIATION INDUCED BY AUXIN INHIBITORS", 1 January 1992, BOTANICA ACTA, STUTTGART, DE, PAGE(S) 121 - 126, ISSN: 0932-8629, XP009131587
HEUPEL THORSTEN ET AL: "The auxin antagonist p-chlorophenoxyisobutyric acid abolishes polar distribution of DNA synthesizing cells within the Meristem of Riella helicophylla", 1 January 1995, JOURNAL OF PLANT PHYSIOLOGY, FISCHER, STUTTGART, DE, PAGE(S) 757 - 759, ISSN: 0176-1617, XP009131591
MURASHIGE T AND SKOOG F: "A revised medium for rapid growth and bio assays with Tobacco tissue cultures", PHYSIOLOGIA PLANTARUM, vol. 15, 1962, pages 473 - 497, XP002577845
DRAKE PASCAL M W ET AL: "Rhizosecretion of a monoclonal antibody protein complex from transgenic tobacco roots.", May 2003, PLANT MOLECULAR BIOLOGY, VOL. 52, NR. 1, PAGE(S) 233-241, ISSN: 0167-4412, XP002577846
DRAKE PASCAL M W ET AL: "Development of rhizosecretion as a production system for recombinant proteins from hydroponic cultivated tobacco", October 2009, FASEB JOURNAL, VOL. 23, NR. 10, PAGE(S) 3581-3589, ISSN: 0892-6638, XP002577522
Attorney, Agent or Firm:
CAMPBELL, Patrick, John, Henry et al. (14 South SquareGray's Inn, London WC1R 5JJ, GB)
Download PDF: