Title:
PRODUCTION INTERMEDIATE OF (S)-2-[3-(N-&lcub [4-(4-FLUOROPHENOXY)PHENYL]METHYL&rcub CARBAMOYL)-4-METHOXYPHENYLMETHYL]BUTANOIC ACID
Document Type and Number:
WIPO Patent Application WO/2006/093354
Kind Code:
A1
Abstract:
Disclosed are a novel production intermediate of (S)-2-[3-(N-&lcub [4-(4-fluorophenoxy)phenyl]methyl&rcub carbamoyl)-4-methoxyphenylmethyl]butanoic acid (compound 1), and a method for producing the same. Specifically disclosed is benzyl 5-&lcub (1S,2S)-3-[(S)-4-benzyl-2-oxo-1,3-oxazolidine-3-yl]-2- ethyl-1-hydroxy-3-oxopropyl&rcub -2-methoxybenzoate as a novel production intermediate or a hydrate thereof. Also specifically disclosed are a method for producing such a production intermediate, and a method for commercially advantageously producing the above-mentioned compound 1 by using such a novel production intermediate.
Inventors:
KIMURA TETSUYA (JP)
ARAYA ICHIRO (JP)
KOIKE TOMOMI (JP)
ARAYA ICHIRO (JP)
KOIKE TOMOMI (JP)
Application Number:
PCT/JP2006/304673
Publication Date:
September 08, 2006
Filing Date:
March 03, 2006
Export Citation:
Assignee:
KYORIN SEIYAKU KK (JP)
KIMURA TETSUYA (JP)
ARAYA ICHIRO (JP)
KOIKE TOMOMI (JP)
KIMURA TETSUYA (JP)
ARAYA ICHIRO (JP)
KOIKE TOMOMI (JP)
International Classes:
C07C231/12; A61K31/195; A61P3/06; C07C235/48; C07D263/26
Domestic Patent References:
| WO2000075103A1 | 2000-12-14 |
Other References:
OGATA Y.: "Yuki Kagobutsu no Sanka to Kangen", 1 April 1964, NANKODO CO., LTD., pages: 585, XP003004047
Attorney, Agent or Firm:
Minoura, Kiyoshi (2-2 Kudankita, 3-chom, Chiyoda-ku Tokyo 73, JP)
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