Title:
PRODUCTION METHOD AND PRODUCTION INTERMEDIATE FOR GUANOSINE-3',5'-BISDIPHOSPHATE
Document Type and Number:
WIPO Patent Application WO/2019/156240
Kind Code:
A1
Abstract:
The present invention relates to a production method and a production intermediate for guanosine-3',5'-bisdiphosphate.
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Inventors:
SEIO KOHJI (JP)
MASAKI YOSHIAKI (JP)
OHNO KENTARO (JP)
TOMORI TAKAHITO (JP)
MASAKI YOSHIAKI (JP)
OHNO KENTARO (JP)
TOMORI TAKAHITO (JP)
Application Number:
PCT/JP2019/004725
Publication Date:
August 15, 2019
Filing Date:
February 08, 2019
Export Citation:
Assignee:
TOKYO INST TECH (JP)
International Classes:
C07H19/20
Domestic Patent References:
| WO2009116044A2 | 2009-09-24 |
Foreign References:
| JPS5278897A | 1977-07-02 |
Other References:
SCHATTENKERK, C. ET AL.: "Synthesis of riboguanosine pentaphosphate ppprGpp (Magic Spot II) via a phosphotriester approach", NUCLEIC ACIDS RESEARCH, vol. 13, no. 10, 1985, pages 3635 - 3649, XP055629195, ISSN: 0305-1048, DOI: 10.1093/nar/13.10.3635
BENNETT, G. N. ET AL.: "Guanosine tetraphosphate and its analogs. Chemical synthesis of guanosine 3',5'-dipyrophosphate, deoxyguanosine 3',5'- dipyrophosphate, guanosine 2',5'- bis(methylenediphosphonate), and guanosine 3', 5' bis (methy lenediphosphonate", BIOCHEMISTRY, vol. 15, no. 21, 1976, pages 4623 - 4628, XP002408426, ISSN: 0006-2960, DOI: 10.1021/bi00666a012
MAEKAWA M. ET AL., NAT PLANTS, vol. 1, 2015, pages 15167
IHARA Y. ET AL., PLANT SIGNAL BEHAV., vol. 11, no. 2, 2016, pages el 132966
SIMONCSITS A ET AL., BIOCHIM. BIOPHYS. ACTA, vol. 340, 1974, pages 509 - 515
CHIN, S. A.TAN, W. J.CHUA K. L.LAM, Y., BIOORG. MED. CHEM., vol. 18, 2010, pages 6657 - 6665
See also references of EP 3750906A4
BENNETT, G. N. ET AL.: "Guanosine tetraphosphate and its analogs. Chemical synthesis of guanosine 3',5'-dipyrophosphate, deoxyguanosine 3',5'- dipyrophosphate, guanosine 2',5'- bis(methylenediphosphonate), and guanosine 3', 5' bis (methy lenediphosphonate", BIOCHEMISTRY, vol. 15, no. 21, 1976, pages 4623 - 4628, XP002408426, ISSN: 0006-2960, DOI: 10.1021/bi00666a012
MAEKAWA M. ET AL., NAT PLANTS, vol. 1, 2015, pages 15167
IHARA Y. ET AL., PLANT SIGNAL BEHAV., vol. 11, no. 2, 2016, pages el 132966
SIMONCSITS A ET AL., BIOCHIM. BIOPHYS. ACTA, vol. 340, 1974, pages 509 - 515
CHIN, S. A.TAN, W. J.CHUA K. L.LAM, Y., BIOORG. MED. CHEM., vol. 18, 2010, pages 6657 - 6665
See also references of EP 3750906A4
Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
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