Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
PRODUCTION OF ROSMARINIC ACID FROM SPEARMINT AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2008/090474
Kind Code:
A3
Abstract:
The present invention provides plants and plant tissues of spearmint (Mentha spicata) with enhanced rosmarinic acid levels, and extracts derived there from. Methods and compositions for production and use of rosmarinic acid from spearmint as a nutraceutical are also provided. In particular, an edible beverage derived from plant tissues of spearmint that comprise more than 77.5 mg/g rosmarinic acid on a dry weight basis, is provided, as well as methods for making such a beverage and for using it to treat an inflammatory or infectious disease.

Inventors:
KOTT LAIMA (CA)
FLETCHER RON (CA)
Application Number:
PCT/IB2008/000978
Publication Date:
April 21, 2011
Filing Date:
January 23, 2008
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
UNIV GUELPH (CA)
KOTT LAIMA (CA)
FLETCHER RON (CA)
International Classes:
C12N5/04; A01H1/02; A01H1/04; A01H5/00; A01H5/10; A23F3/00; A23F3/40; A23L2/52; A23L27/10; A61K31/194; A61K36/534; C12P7/62
Other References:
FLETCHER R. S. ET AL.: "Proc. WOCMAPIII. Vol. 6: Traditional Medicine & Nutraceuticals.", ACTA HORT, vol. 680, March 2005 (2005-03-01), pages 31 - 36
CARNAT AP. ET AL.: "The aromatic and polyphenolic composition of lemon balm (Melissa officinalis L. subsp. officinalis) tea", PHARMACUETICA ACTA HELVETIAE, vol. 72, 1998, pages 301 - 305
TAKANA ET AL.: "Extract of Perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits seasonal allergic rhinoconjunctivitis in humans", EXP. BIOL. MED., vol. 229, 2004, pages 247 - 255
IUVONE ET AL.: "The spice sage and its active ingredient rosmarinic acid protect PC 12 cells from amyloid-beta peptide-induced neurotoxicity", J. PHARM. EXP. THER., vol. 317, 2006, pages 1143 - 114
PETERSEN M. ET AL.: "Molecules of interest: Rosmarinic acid.", PHYTOCHEMISTRY, vol. 62, 2003, pages 121 - 127
VOWLES A.: "In mint condition", AT GUELPH (FEATURES), vol. 51, no. 10, 23 May 2007 (2007-05-23), Retrieved from the Internet [retrieved on 20080829]
Download PDF: