Title:
PRODUCTION OF TETANUS, DIPHTHERIA, AND PERTUSSIS TOXINS AND TOXOIDS USING FERMENTATION MEDIA CONTAINING NO COMPONENTS OF ANIMAL OR SOY ORIGIN
Document Type and Number:
WIPO Patent Application WO2006042542
Kind Code:
A3
Abstract:
The present invention discloses that non-animal and non-soy based result in increased growth of C.tetani, C.diphteriae, and B.pertussis and result in equivalent or increased yield of tetanus toxin, diphteria toxin and pertussis toxin, respectively, compared to cultivation of the bacteria in media containing animal-derived or soy-derived proteinaceous material. Preferably the proteinaceous hydrolysates are derived from wheat, a mixture of rice and wheat, from potato, or from yeast.
Inventors:
AAMAND SUSANNE (DK)
PETERSEN JESPER WESTPHAL (DK)
PETERSEN JESPER WESTPHAL (DK)
Application Number:
PCT/DK2005/000636
Publication Date:
December 07, 2006
Filing Date:
October 05, 2005
Export Citation:
Assignee:
STATENS SERUMINSTITUT (DK)
AAMAND SUSANNE (DK)
PETERSEN JESPER WESTPHAL (DK)
AAMAND SUSANNE (DK)
PETERSEN JESPER WESTPHAL (DK)
International Classes:
C12N1/20; A61K39/08
Domestic Patent References:
| WO1998054296A1 | 1998-12-03 | |||
| WO2005056773A1 | 2005-06-23 | |||
| WO2001005997A2 | 2001-01-25 | |||
| WO2004083400A2 | 2004-09-30 |
Other References:
"scientific research 2003/2004 / Fluka catalogue", 2003, FLUKA CHEMIE GMBH, XP002377083
LARKIN M: "Vegetarian option for biotech drugs could cut BSE risk", LANCET INFECTIOUS DISEASES, US, vol. 2, no. 12, December 2002 (2002-12-01), pages 715, XP004816264, ISSN: 1473-3099
WHITMER M E ET AL: "DEVELOPMENT OF IMPROVED DEFINED MEDIA FOR CLOSTRIDIUM BOTULINUM SEROTYPES A, B, AND E", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, WASHINGTON,DC, US, vol. 54, no. 3, March 1988 (1988-03-01), pages 753 - 759, XP008040512, ISSN: 0099-2240
LARKIN M: "Vegetarian option for biotech drugs could cut BSE risk", LANCET INFECTIOUS DISEASES, US, vol. 2, no. 12, December 2002 (2002-12-01), pages 715, XP004816264, ISSN: 1473-3099
WHITMER M E ET AL: "DEVELOPMENT OF IMPROVED DEFINED MEDIA FOR CLOSTRIDIUM BOTULINUM SEROTYPES A, B, AND E", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, WASHINGTON,DC, US, vol. 54, no. 3, March 1988 (1988-03-01), pages 753 - 759, XP008040512, ISSN: 0099-2240
Download PDF:
Previous Patent: SUNROOF DEVICE FOR MOTOR VEHICLES
Next Patent: VALVE FOR USE IN A REFRIGERATION SYSTEM
Next Patent: VALVE FOR USE IN A REFRIGERATION SYSTEM