Title:
PROMOTER SUBSTITUTION FOR IMMUNOGLOBULIN THERAPY
Document Type and Number:
WIPO Patent Application WO2006029005
Kind Code:
A3
Abstract:
The present invention involves the identification of Bright as involved in immunoglobulin production, and the targeting of that function for the treatment of disease states associated with pathologic immunoglobulin production. Also provided are methods of identifying candidate substances with Bright-inhibitory activity.
Inventors:
WEBB CAROL F (US)
Application Number:
PCT/US2005/031397
Publication Date:
June 22, 2006
Filing Date:
September 02, 2005
Export Citation:
Assignee:
OKLAHOMA MED RES FOUND (US)
WEBB CAROL F (US)
WEBB CAROL F (US)
International Classes:
C12N15/85; A61K48/00; C07K16/46
Foreign References:
| US5661016A | 1997-08-26 | |||
| US20040093622A1 | 2004-05-13 | |||
| US20040073957A1 | 2004-04-15 |
Other References:
HOWARD V ET AL: "Stem cell transplants for patients with X-linked agammaglobulinemia", CLINICAL IMMUNOLOGY 01 MAY 2003 UNITED STATES, vol. 107, no. 2, 1 May 2003 (2003-05-01), pages 98 - 102, XP002366392, ISSN: 1521-6616
MILILI MICHELE ET AL: "A new case of autosomal recessive agammaglobulinaemia with impaired pre-B cell differentiation due to a large deletion of the IGH locus", EUROPEAN JOURNAL OF PEDIATRICS, vol. 161, no. 9, September 2002 (2002-09-01), pages 479 - 484, XP002366635, ISSN: 0340-6199
MILILI MICHELE ET AL: "A new case of autosomal recessive agammaglobulinaemia with impaired pre-B cell differentiation due to a large deletion of the IGH locus", EUROPEAN JOURNAL OF PEDIATRICS, vol. 161, no. 9, September 2002 (2002-09-01), pages 479 - 484, XP002366635, ISSN: 0340-6199
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