Title:
PROPANE-1,3-DIONE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2002/002533
Kind Code:
A1
Abstract:
Medicinal compositions, in particular, GnRH receptor antagonists comprising propane-1,3-dione derivatives represented by the following general formula (1) as the active ingredient; and novel propane-1,3-dione derivatives having a GnRH antagonism: general formula (1).
Inventors:
HIRANO MASAAKI (JP)
KAWAMINAMI EIJI (JP)
TOYOSHIMA AKIRA (JP)
MORITOMO HIROYUKI (JP)
SEKI NORIO (JP)
WAKAYAMA RYUTARO (JP)
OKADA MINORU (JP)
KUSAYAMA TOSHIYUKI (JP)
KAWAMINAMI EIJI (JP)
TOYOSHIMA AKIRA (JP)
MORITOMO HIROYUKI (JP)
SEKI NORIO (JP)
WAKAYAMA RYUTARO (JP)
OKADA MINORU (JP)
KUSAYAMA TOSHIYUKI (JP)
Application Number:
PCT/JP2001/005813
Publication Date:
January 10, 2002
Filing Date:
July 04, 2001
Export Citation:
Assignee:
YAMANOUCHI PHARMA CO LTD (JP)
HIRANO MASAAKI (JP)
KAWAMINAMI EIJI (JP)
TOYOSHIMA AKIRA (JP)
MORITOMO HIROYUKI (JP)
SEKI NORIO (JP)
WAKAYAMA RYUTARO (JP)
OKADA MINORU (JP)
KUSAYAMA TOSHIYUKI (JP)
HIRANO MASAAKI (JP)
KAWAMINAMI EIJI (JP)
TOYOSHIMA AKIRA (JP)
MORITOMO HIROYUKI (JP)
SEKI NORIO (JP)
WAKAYAMA RYUTARO (JP)
OKADA MINORU (JP)
KUSAYAMA TOSHIYUKI (JP)
International Classes:
A61K31/4184; A61K31/422; A61K31/427; A61K31/428; A61K31/4439; A61K31/454; A61K31/4725; A61K31/506; A61K31/5377; A61P5/24; A61P35/00; C07D235/06; C07D235/12; C07D277/64; C07D277/84; C07D339/06; C07D401/06; C07D401/12; C07D401/14; C07D403/06; C07D403/12; C07D405/06; C07D405/12; C07D413/14; C07D417/06; C07D417/12; C07D417/14; C07D471/04; C07D487/04; (IPC1-7): C07D235/06; C07D277/64; C07D401/06; C07D401/12; C07D401/14; C07D403/12; C07D405/06; C07D405/12; C07D405/14; C07D409/06; C07D409/12; C07D409/14; C07D413/12; C07D417/12; C07D471/04; A61K31/4184; A61K31/422; A61K31/427; A61K31/428; A61K31/4439; A61K31/454; A61K31/4725; A61K31/506; A61K31/5377; A61P5/24; A61P35/00
Domestic Patent References:
| WO1995028405A1 | 1995-10-26 |
Foreign References:
| JP2000095767A | 2000-04-04 | |||
| US4062686A | 1977-12-13 | |||
| EP0368327A2 | 1990-05-16 |
Other References:
HOLIK MIROSLAV ET AL.: "Spectroscopic investigation of beta-dicarbonyl compounds. Part III. Proton-NMR study of transfer of substituent effects in 2-dibenzoylmethylene-3-ethylbenzothiazolines and -selezazolines", COLLECT. CZECH. CHEM. COMMUN., vol. 43, no. 3, 1978, pages 739 - 745, XP002942967
Attorney, Agent or Firm:
Nagai, Shozo c/o Yamanouchi Pharmaceutical Co. (Ltd. Patent Department 17-1 Hasune 3-chome Itabashi-ku, Tokyo, JP)
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