Title:
PROPHYLACTIC AGENT FOR PNEUMOCOCCAL INFECTION
Document Type and Number:
WIPO Patent Application WO/2015/133638
Kind Code:
A1
Abstract:
[Problem] To provide a composition for preventing the infection by a pneumococcus and preventing or inhibiting the infection from becoming severe during the occurrence of the infection.
[Solution] A fermentation product of Lactobacillus delbrueckii ssp. Bulgaricus strain OLL1073R-1 which preferably contains living bodies of the bacterium, is used as a prophylactic agent for pneumococcal infection. The fermentation product is, for example, yoghurt or a lactic acid bacterium beverage. When a normal person ingests the fermentation product, it becomes possible to prevent the infection by a pneumococcus and to prevent or inhibit the infection from becoming severe during the occurrence of the infection.
Inventors:
NAKAMURA SHIGEKI (JP)
OSHIMA KAZUHIRO (JP)
KOHNO SHIGERU (JP)
IKEAMI SHUJI (JP)
OSHIMA KAZUHIRO (JP)
KOHNO SHIGERU (JP)
IKEAMI SHUJI (JP)
Application Number:
PCT/JP2015/056755
Publication Date:
September 11, 2015
Filing Date:
March 07, 2015
Export Citation:
Assignee:
MEIJI CO LTD (JP)
International Classes:
A61K35/74; A61P11/00; A61P31/04; C12N1/20; C12R1/225; C12R1/46
Other References:
MASAYA MAKINO ET AL.: "Lactobacillus bulgaricus Sansei Tatotai no Men'eki Kino Chosetsu Sayo", MILK SCIENCE, vol. 53, no. 3, 2004, pages 161 - 164
MASAYA MAKINO: "Immunostimulatory effects of yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 and its exopolysaccharides", MILK SCIENCE, vol. 58, no. 2, 2009, pages 35 - 40
MASUMITSU HATTA ET AL.: "Saikin - Shinkin Kansen Bogyo ni Okeru Interferon no Yakuwari", INFLAMMATION & IMMUNOLOGY, vol. 15, no. 2, 2007, pages 197 - 201
MASAKAZU KITA: "Hi Virus-sei Kansensho ni Okeru IFN-y no Yakuwari", JAPANESE JOURNAL OF CLINICAL MEDICINE, vol. 64, no. 7, 2006, pages 1269 - 1274
MASAMICHI KAWASHIMA ET AL.: "Oshoku Budo Kyukin, Haien Kyukin, Ryokunokin, Listeria Fukumaku-nai Kansen ni Taisuru Sankosei Nyusan Kankin Maeshori no Bogyo Koka", MEDICINE AND BIOLOGY, vol. 117, no. 2, 1988, pages 119 - 122
VILLENA, J. ET AL.: "Lactic acid bacteria in the prevention of pneumococcal respiratory infection: future opportunities and challenges", INT. IMMUNOPHARMACOL., vol. 11, no. 11, 2011, pages 1633 - 1645, XP028326740, ISSN: 1567-5769
TANAKA, A. ET AL.: "Lactobacillus pentosus strain b240 suppresses pneumonia induced by Streptococcus pneumoniae in mice", LETT. APPL. MICROBIOL., vol. 53, no. 1, 2011, pages 35 - 43
RACEDO, S. ET AL.: "Influence of yogurt consumption on the respiratory immune response", FOOD AND AGRICULTURAL IMMUNOLOGY, vol. 20, no. 3, 2009, pages 231 - 244, XP055222924, ISSN: 0954-0105
MASAYA MAKINO: "Immunostimulatory effects of yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 and its exopolysaccharides", MILK SCIENCE, vol. 58, no. 2, 2009, pages 35 - 40
MASUMITSU HATTA ET AL.: "Saikin - Shinkin Kansen Bogyo ni Okeru Interferon no Yakuwari", INFLAMMATION & IMMUNOLOGY, vol. 15, no. 2, 2007, pages 197 - 201
MASAKAZU KITA: "Hi Virus-sei Kansensho ni Okeru IFN-y no Yakuwari", JAPANESE JOURNAL OF CLINICAL MEDICINE, vol. 64, no. 7, 2006, pages 1269 - 1274
MASAMICHI KAWASHIMA ET AL.: "Oshoku Budo Kyukin, Haien Kyukin, Ryokunokin, Listeria Fukumaku-nai Kansen ni Taisuru Sankosei Nyusan Kankin Maeshori no Bogyo Koka", MEDICINE AND BIOLOGY, vol. 117, no. 2, 1988, pages 119 - 122
VILLENA, J. ET AL.: "Lactic acid bacteria in the prevention of pneumococcal respiratory infection: future opportunities and challenges", INT. IMMUNOPHARMACOL., vol. 11, no. 11, 2011, pages 1633 - 1645, XP028326740, ISSN: 1567-5769
TANAKA, A. ET AL.: "Lactobacillus pentosus strain b240 suppresses pneumonia induced by Streptococcus pneumoniae in mice", LETT. APPL. MICROBIOL., vol. 53, no. 1, 2011, pages 35 - 43
RACEDO, S. ET AL.: "Influence of yogurt consumption on the respiratory immune response", FOOD AND AGRICULTURAL IMMUNOLOGY, vol. 20, no. 3, 2009, pages 231 - 244, XP055222924, ISSN: 0954-0105
Attorney, Agent or Firm:
SHIMURA HISASHI (JP)
Shoji Shimura (JP)
Shoji Shimura (JP)
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