Title:
PROPHYLACTIC, AMELIORATING OR THERAPEUTIC AGENT FOR RETINAL DISEASES
Document Type and Number:
WIPO Patent Application WO/2013/129315
Kind Code:
A1
Abstract:
A prophylactic, ameliorating or therapeutic agent for retinal diseases, which comprises geranylgeranylacetone as mentioned in item (a), (b) or (c) below, can inhibit the cell death of retinal cells directly to thereby prevent, ameliorate or treat retinal diseases radically: (a) a mixture of 5E,9E,13E-geranylgeranylacetone with 5Z,9E,13E-geranylgeranylacetone, wherein 5E,9E,13E-geranylgeranylacetone is contained in the mixture in an amount of 80 wt% or more; (b) 5E,9E,13E-geranylgeranylacetone alone; and (c) 5Z,9E,13E-geranylgeranylacetone alone.
Inventors:
KUROSE TAKAHIRO (JP)
MIYANO TAKAYUKI (JP)
KATO MARIYO (JP)
TAKAI YOSHIHIRO (JP)
MIYANO TAKAYUKI (JP)
KATO MARIYO (JP)
TAKAI YOSHIHIRO (JP)
Application Number:
PCT/JP2013/054774
Publication Date:
September 06, 2013
Filing Date:
February 25, 2013
Export Citation:
Assignee:
ROHTO PHARMA (JP)
International Classes:
A61K31/121; A61K9/08; A61K47/02; A61P27/02; A61P27/06
Domestic Patent References:
| WO2012031028A2 | 2012-03-08 |
Foreign References:
| JPH08133967A | 1996-05-28 | |||
| JP2009507770A | 2009-02-26 | |||
| JPH06192073A | 1994-07-12 |
Other References:
ISHII, Y. ET AL.: "Investigative Ophthalmology & Visual Science", vol. 44, no. 5, 2003, pages 1982 - 1992
HARADA, C. ET AL.: "Molecular Vision", vol. 13, 2007, pages 1601 - 1607
TANITO, M. ET AL.: "The Journal of Neuroscience", vol. 25, no. 9, 2005, pages 2396 - 2404
MURAKAMI, M. ET AL., JAPAN. J. PHARAMACOL., vol. 33, 1983, pages 549 - 556
HARADA, C. ET AL.: "Molecular Vision", vol. 13, 2007, pages 1601 - 1607
TANITO, M. ET AL.: "The Journal of Neuroscience", vol. 25, no. 9, 2005, pages 2396 - 2404
MURAKAMI, M. ET AL., JAPAN. J. PHARAMACOL., vol. 33, 1983, pages 549 - 556
Attorney, Agent or Firm:
IWATANI, Ryo (JP)
Tatsu Iwatani (JP)
Tatsu Iwatani (JP)
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Claims: