Title:
PROPHYLACTIC OR THERAPEUTIC AGENT FOR ALLERGIC DISEASES
Document Type and Number:
WIPO Patent Application WO/2022/215566
Kind Code:
A1
Abstract:
[Problem] The present invention addresses the problem of discovering a molecule that is selectively expressed in mast cells and providing a prophylactic or therapeutic agent for allergic diseases. [Solution] This prophylactic or therapeutic agent is for allergic diseases and comprises an anti-Clec12b antibody or an antibody fragment thereof.
Inventors:
SHIBUYA AKIRA (JP)
KANEMARU KAZUMASA (JP)
IIJIMA AYANA (JP)
KANEMARU KAZUMASA (JP)
IIJIMA AYANA (JP)
Application Number:
PCT/JP2022/014790
Publication Date:
October 13, 2022
Filing Date:
March 28, 2022
Export Citation:
Assignee:
UNIV TSUKUBA (JP)
International Classes:
A61K39/395; A61P17/00; A61P17/04; A61P37/08; A61P43/00; C07K16/28; C12N15/13
Domestic Patent References:
| WO2018224615A1 | 2018-12-13 | |||
| WO2020120592A1 | 2020-06-18 |
Foreign References:
| JP2017501744A | 2017-01-19 | |||
| JP2008502368A | 2008-01-31 |
Other References:
SABRINA C. HOFFMANN, CAROLA SCHELLACK, SONJA TEXTOR, STEPHANIE KONOLD, DEBORA SCHMITZ, ADELHEID CERWENKA, STEFAN PFLANZ, CARSTEN W: "Identification of CLEC12B, an Inhibitory Receptor on Myeloid Cells", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, US, vol. 282, no. 31, 3 August 2007 (2007-08-03), US , pages 22370 - 22375, XP055424204, ISSN: 0021-9258, DOI: 10.1074/jbc.M704250200
SENTAN IGAKUSHA, TOKYO ; 1 January 2021 (2021-01-01), IIJIMA AYANA, KANEMARU KAZUMASA. SHIBUYA AKIRA: "Suppression of house dustmite-induced dermatitis by C-type lectin receptor Clec10a.", XP009540364
KAZUMASA KANAMARU, SATOKO TAHARA, AKIRA SHIBUYA: "Control of allergic diseases targeting mast cells", ENSHO TO MEN'EKI - INFLAMMATION AND IMMUNOLOGY, SENTAN IGAKUSHA, TOKYO, JP, vol. 22, no. 1, 1 January 2014 (2014-01-01), JP , pages 47 - 53, XP009540425, ISSN: 0918-8371
IIJIMA AYANA; KANEMARU KAZUMASA; WANG YAQIU; NABEKURA TSUKASA; NAKAMURA YOSHIYUKI; FUJISAWA YASUHIRO; MORI DAIKI; OHMURAYA MASAKI;: "Selective expression of a C-type lectin receptor, Clec12b, on skin mast cells", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ELSEVIER, AMSTERDAM NL, vol. 561, 18 May 2021 (2021-05-18), Amsterdam NL , pages 101 - 105, XP086582912, ISSN: 0006-291X, DOI: 10.1016/j.bbrc.2021.04.097
25 March 2022 (2022-03-25), IIJIMA, AYANA; KANEMURA KAZUMASA, SHIBUYA, AKIRA: "Selective expression of a C-type lectin receptor, Clec12b, on skin mast cells", XP009540363
SENTAN IGAKUSHA, TOKYO ; 1 January 2021 (2021-01-01), IIJIMA AYANA, KANEMARU KAZUMASA. SHIBUYA AKIRA: "Suppression of house dustmite-induced dermatitis by C-type lectin receptor Clec10a.", XP009540364
KAZUMASA KANAMARU, SATOKO TAHARA, AKIRA SHIBUYA: "Control of allergic diseases targeting mast cells", ENSHO TO MEN'EKI - INFLAMMATION AND IMMUNOLOGY, SENTAN IGAKUSHA, TOKYO, JP, vol. 22, no. 1, 1 January 2014 (2014-01-01), JP , pages 47 - 53, XP009540425, ISSN: 0918-8371
IIJIMA AYANA; KANEMARU KAZUMASA; WANG YAQIU; NABEKURA TSUKASA; NAKAMURA YOSHIYUKI; FUJISAWA YASUHIRO; MORI DAIKI; OHMURAYA MASAKI;: "Selective expression of a C-type lectin receptor, Clec12b, on skin mast cells", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ELSEVIER, AMSTERDAM NL, vol. 561, 18 May 2021 (2021-05-18), Amsterdam NL , pages 101 - 105, XP086582912, ISSN: 0006-291X, DOI: 10.1016/j.bbrc.2021.04.097
25 March 2022 (2022-03-25), IIJIMA, AYANA; KANEMURA KAZUMASA, SHIBUYA, AKIRA: "Selective expression of a C-type lectin receptor, Clec12b, on skin mast cells", XP009540363
Attorney, Agent or Firm:
SSINPAT PATENT FIRM (JP)
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